Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 1761
LigandPNGBDBM13954(3-({5-[(N-Acetyl-3-{4-[(carboxycarbonyl)(2-carboxy...)
Affinity DataKi:  22nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13954(3-({5-[(N-Acetyl-3-{4-[(carboxycarbonyl)(2-carboxy...)
Affinity DataKi:  49nM ΔG°:  -41.3kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
LigandPNGBDBM13953(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]naphth...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13953(2-({4-[2-acetamido-2-(pentylcarbamoyl)ethyl]naphth...)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  3.90E+4nM ΔG°:  -24.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  4.40E+4nM ΔG°:  -24.6kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13951(CHEMBL65459 | 2-[(2,3-dimethylphenyl)amidoformic a...)
Affinity DataKi:  1.64E+5nM ΔG°:  -21.4kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed
LigandPNGBDBM13951(CHEMBL65459 | 2-[(2,3-dimethylphenyl)amidoformic a...)
Affinity DataKi:  2.93E+5nM ΔG°:  -20.0kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMed