Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50013117
TargetAldo-keto reductase family 1 member A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126780(Cyano-[5-fluoro-1-(4-methyl-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126780(Cyano-[5-fluoro-1-(4-methyl-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 75nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126783(Cyano-[5-fluoro-1-(4-methoxy-benzyl)-2-oxo-2,3-dih...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126777(Cyano-[5-fluoro-1-(4-fluoro-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126777(Cyano-[5-fluoro-1-(4-fluoro-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 130nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126782((1-Benzyl-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl...)
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126785([5-Bromo-1-(4-methyl-benzyl)-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126774(Cyano-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)-a...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126774(Cyano-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)-a...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126773(Cyano-(5-fluoro-2-oxo-1-propyl-2,3-dihydro-1H-indo...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126781(Cyano-[5-fluoro-2-oxo-1-(4-trifluoromethyl-benzyl)...)
Affinity DataIC50: 280nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126776((5-Bromo-2-oxo-2,3-dihydro-1H-indol-3-yl)-cyano-ac...)
Affinity DataIC50: 380nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126778(Cyano-(5-fluoro-1-methyl-2-oxo-2,3-dihydro-1H-indo...)
Affinity DataIC50: 390nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126777(Cyano-[5-fluoro-1-(4-fluoro-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 490nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126787(Cyano-[2-oxo-1-(4-trifluoromethyl-benzyl)-2,3-dihy...)
Affinity DataIC50: 570nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126775(Cyano-[1-(4-fluoro-benzyl)-2-oxo-2,3-dihydro-1H-in...)
Affinity DataIC50: 570nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126784(Cyano-[1-(4-methoxy-benzyl)-2-oxo-2,3-dihydro-1H-i...)
Affinity DataIC50: 630nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126791(Cyano-[1-(4-methyl-benzyl)-2-oxo-2,3-dihydro-1H-in...)
Affinity DataIC50: 640nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126791(Cyano-[1-(4-methyl-benzyl)-2-oxo-2,3-dihydro-1H-in...)
Affinity DataIC50: 640nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126780(Cyano-[5-fluoro-1-(4-methyl-benzyl)-2-oxo-2,3-dihy...)
Affinity DataIC50: 690nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126789(Cyano-(2-oxo-2,3-dihydro-1H-indol-3-yl)-acetic aci...)
Affinity DataIC50: 850nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126788(Cyano-(5-nitro-2-oxo-2,3-dihydro-1H-indol-3-yl)-ac...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126779([1-(2-Chloro-ethyl)-5-fluoro-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 1.34E+3nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 2.32E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126786((1-Benzyl-2-oxo-2,3-dihydro-1H-indol-3-yl)-cyano-a...)
Affinity DataIC50: 3.20E+3nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126791(Cyano-[1-(4-methyl-benzyl)-2-oxo-2,3-dihydro-1H-in...)
Affinity DataIC50: 3.57E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126790(Cyano-(5-methoxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-...)
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50126774(Cyano-(5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)-a...)
Affinity DataIC50: 6.79E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 8.32E+3nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 8.32E+3nMAssay Description:In vitro inhibitory activity against aldose reductase (ALR2) from rat lens extraction.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSorbitol dehydrogenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 3.56E+4nMAssay Description:In vitro inhibitory activity against sorbitol dehydrogenase (SD) from sheep liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutathione reductase(Baker's yeast)
Università

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 4.88E+4nMAssay Description:In vitro inhibitory activity against glutathione reductase (GR) from bakers yeastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed