Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50013269
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  0.310nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579(8-CAC | CHEMBL58646 | (6S,11R)-3-Cyclopropylmethyl...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128408((1R,9R,13R)-10-(cyclopropylmethyl)-1,13-dimethyl-1...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579(8-CAC | CHEMBL58646 | (6S,11R)-3-Cyclopropylmethyl...)
Affinity DataKi:  0.530nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50000091(EKC | EKC(-) | CHEMBL279968 | 3-Cyclopropylmethyl-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097586(3-cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50000091(EKC | EKC(-) | CHEMBL279968 | 3-Cyclopropylmethyl-...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128407(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  0.850nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128408((1R,9R,13R)-10-(cyclopropylmethyl)-1,13-dimethyl-1...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50001023((2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128405(N-((6S,11R)-3-Cyclopropylmethyl-6-ethyl-11-methyl-...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097586(3-cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128411(4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,13R,1...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128407(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50000091(EKC | EKC(-) | CHEMBL279968 | 3-Cyclopropylmethyl-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128413(N-[4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,17...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128410(10-amino-4-cyclopropylmethyl-17-hydroxy-(1S,5R,13R...)
Affinity DataKi:  5.60nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128410(10-amino-4-cyclopropylmethyl-17-hydroxy-(1S,5R,13R...)
Affinity DataKi:  5.80nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128405(N-((6S,11R)-3-Cyclopropylmethyl-6-ethyl-11-methyl-...)
Affinity DataKi:  6.10nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097579(8-CAC | CHEMBL58646 | (6S,11R)-3-Cyclopropylmethyl...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128413(N-[4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,17...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097586(3-cyclopropylmethyl-6-ethyl-11-methyl-1-oxo-1,2,3,...)
Affinity DataKi:  9.80nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128408((1R,9R,13R)-10-(cyclopropylmethyl)-1,13-dimethyl-1...)
Affinity DataKi:  9.80nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataKi:  11nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128411(4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,13R,1...)
Affinity DataKi:  22nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128407(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  37nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128405(N-((6S,11R)-3-Cyclopropylmethyl-6-ethyl-11-methyl-...)
Affinity DataKi:  52nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128411(4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,13R,1...)
Affinity DataKi:  110nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128404(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  130nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128412(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  200nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128404(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  240nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128413(N-[4-cyclopropylmethyl-17-hydroxy-14-oxo-(1S,5R,17...)
Affinity DataKi:  420nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097577(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  460nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128412(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  550nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128409(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  570nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097577(3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexa...)
Affinity DataKi:  740nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128409(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  820nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128410(10-amino-4-cyclopropylmethyl-17-hydroxy-(1S,5R,13R...)
Affinity DataKi:  880nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128406((1S,9S,13S)-10-(cyclopropylmethyl)-1,13-dimethyl-1...)
Affinity DataKi:  900nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128404(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  1.70E+3nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128406((1S,9S,13S)-10-(cyclopropylmethyl)-1,13-dimethyl-1...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128409(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  2.40E+3nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128412(N-((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,...)
Affinity DataKi:  6.20E+3nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50128406((1S,9S,13S)-10-(cyclopropylmethyl)-1,13-dimethyl-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed