Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50013280
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128532(5-(7-Chloro-10-methylsulfanyl-3,4-dihydro-1H-pyraz...)
Affinity DataIC50: 2nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128535(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 2.80nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50: 4nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128540(5-(1,3,4,9-Tetrahydro-beta-carbolin-2-ylmethyl)-py...)
Affinity DataIC50: 4nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128538(5-[7-Methoxy-4-(3-nitro-phenyl)-3,4-dihydro-1H-iso...)
Affinity DataIC50: 6nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128533(5-[4-(2,4-Dichloro-phenyl)-6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50: 7nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128535(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 9.80nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128536(5-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 10nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128537(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 12nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128529(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 21nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128537(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 27nMAssay Description:Antibacterial activity against TMP-Resistant Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128529(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128532(5-(7-Chloro-10-methylsulfanyl-3,4-dihydro-1H-pyraz...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128533(5-[4-(2,4-Dichloro-phenyl)-6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128531(5-(7-Benzyl-1-methyl-6-phenyl-3,4-dihydro-1H-pyrro...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128530(5-(6,7-Dimethoxy-1-methyl-3,4-dihydro-1H-isoquinol...)
Affinity DataIC50: 44nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128540(5-(1,3,4,9-Tetrahydro-beta-carbolin-2-ylmethyl)-py...)
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128530(5-(6,7-Dimethoxy-1-methyl-3,4-dihydro-1H-isoquinol...)
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128538(5-[7-Methoxy-4-(3-nitro-phenyl)-3,4-dihydro-1H-iso...)
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128532(5-(7-Chloro-10-methylsulfanyl-3,4-dihydro-1H-pyraz...)
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 75nMAssay Description:Inhibitory activity against TMP-susceptible DHFR from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50: 85nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128536(5-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity of TMP-Resistance DHFR against Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128536(5-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128531(5-(7-Benzyl-1-methyl-6-phenyl-3,4-dihydro-1H-pyrro...)
Affinity DataIC50: 450nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128529(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 520nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128531(5-(7-Benzyl-1-methyl-6-phenyl-3,4-dihydro-1H-pyrro...)
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128530(5-(6,7-Dimethoxy-1-methyl-3,4-dihydro-1H-isoquinol...)
Affinity DataIC50: 670nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128539(5-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-pyrimidi...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128535(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 1.20E+3nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128535(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128537(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128533(5-[4-(2,4-Dichloro-phenyl)-6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50: 1.70E+3nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128533(5-[4-(2,4-Dichloro-phenyl)-6,7-dimethoxy-3,4-dihyd...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antibacterial activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128538(5-[7-Methoxy-4-(3-nitro-phenyl)-3,4-dihydro-1H-iso...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128532(5-(7-Chloro-10-methylsulfanyl-3,4-dihydro-1H-pyraz...)
Affinity DataIC50: 5.20E+3nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128529(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128539(5-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-pyrimidi...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128534(5-(4,11-Dimethyl-1,2,4,11-tetrahydro-pyrido[4,3-a]...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128540(5-(1,3,4,9-Tetrahydro-beta-carbolin-2-ylmethyl)-py...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128537(5-(4-Methoxy-9-methyl-6,9-dihydro-7H-[1,3]dioxolo[...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128530(5-(6,7-Dimethoxy-1-methyl-3,4-dihydro-1H-isoquinol...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128531(5-(7-Benzyl-1-methyl-6-phenyl-3,4-dihydro-1H-pyrro...)
Affinity DataIC50: 1.80E+4nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.90E+4nMAssay Description:Tested for inhibition of TMP-Resistant Dihydrofolate reductase from Staphylococcus aureus 157/4696.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128536(5-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity of TMP-Resistance DHFR against Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50128536(5-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylme...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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