Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50013314
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50129020(ethyl N-{(1R)-1-[(hydroxyamino)carbonyl]-3-methylb...)
Affinity DataKi:  5.10nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50291705((S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquin...)
Affinity DataKi:  6.20nMAssay Description:Inhibition of recombinant human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50171860(((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50129019(ethyl N-{(1R)-4-(2-phentl-ethyl)-amino-1-[(hydroxy...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50129022(ethyl N-{(1s)-4-(2-phentl-ethyl)-amino-1-[(hydroxy...)
Affinity DataKi:  10nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50129019(ethyl N-{(1R)-4-(2-phentl-ethyl)-amino-1-[(hydroxy...)
Affinity DataKi:  24nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50129019(ethyl N-{(1R)-4-(2-phentl-ethyl)-amino-1-[(hydroxy...)
Affinity DataKi:  28nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50129019(ethyl N-{(1R)-4-(2-phentl-ethyl)-amino-1-[(hydroxy...)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50129020(ethyl N-{(1R)-1-[(hydroxyamino)carbonyl]-3-methylb...)
Affinity DataKi:  70nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50129021(ethyl N-{(1s)-1-[(hydroxyamino)carbonyl]-3-methylb...)
Affinity DataKi:  76nMAssay Description:Inhibition of recombinant human tumor necrosis factor-alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50129020(ethyl N-{(1R)-1-[(hydroxyamino)carbonyl]-3-methylb...)
Affinity DataKi:  165nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50129020(ethyl N-{(1R)-1-[(hydroxyamino)carbonyl]-3-methylb...)
Affinity DataKi:  196nMAssay Description:Inhibition of recombinant human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed