Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50035311
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 27nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 42nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130060((R)-N-{(S)-2-(2-fluoro-phenyl)-1-[(S)-4-guanidino-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 160nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130058((R)-N-{(S)-2-(3,4-Difluoro-phenyl)-1-[(S)-4-guanid...)
Affinity DataIC50: 160nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 170nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14514(CHEMBL78053 | (2R)-N-[(1S)-1-{[(2S)-5-carbamimidam...)
Affinity DataIC50: 200nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130062((R)-N-{2-(3-Fluoro-phenyl)-1-[(S)-(S)-4-guanidino-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130058((R)-N-{(S)-2-(3,4-Difluoro-phenyl)-1-[(S)-4-guanid...)
Affinity DataIC50: 210nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130060((R)-N-{(S)-2-(2-fluoro-phenyl)-1-[(S)-4-guanidino-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130064((R)-N-{2-(3-Chloro-phenyl)-1-[(S)-(S)-4-guanidino-...)
Affinity DataIC50: 230nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130056((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 240nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130062((R)-N-{2-(3-Fluoro-phenyl)-1-[(S)-(S)-4-guanidino-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130064((R)-N-{2-(3-Chloro-phenyl)-1-[(S)-(S)-4-guanidino-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14514(CHEMBL78053 | (2R)-N-[(1S)-1-{[(2S)-5-carbamimidam...)
Affinity DataIC50: 290nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50366819(CHEMBL1790570)
Affinity DataIC50: 300nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130056((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 330nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130054((R)-N-{2-(4-Cyano-phenyl)-1-[(S)-(S)-4-guanidino-1...)
Affinity DataIC50: 340nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50366819(CHEMBL1790570)
Affinity DataIC50: 380nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 800nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130054((R)-N-{2-(4-Cyano-phenyl)-1-[(S)-(S)-4-guanidino-1...)
Affinity DataIC50: 900nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130055((S)-3-Cyano-N-[(S)-4-guanidino-1-(thiazole-2-carbo...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130055((S)-3-Cyano-N-[(S)-4-guanidino-1-(thiazole-2-carbo...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130058((R)-N-{(S)-2-(3,4-Difluoro-phenyl)-1-[(S)-4-guanid...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130064((R)-N-{2-(3-Chloro-phenyl)-1-[(S)-(S)-4-guanidino-...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130062((R)-N-{2-(3-Fluoro-phenyl)-1-[(S)-(S)-4-guanidino-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50366819(CHEMBL1790570)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130056((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130060((R)-N-{(S)-2-(2-fluoro-phenyl)-1-[(S)-4-guanidino-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130054((R)-N-{2-(4-Cyano-phenyl)-1-[(S)-(S)-4-guanidino-1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50228753((S)-N*1*-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130065((R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 8.49E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM14514(CHEMBL78053 | (2R)-N-[(1S)-1-{[(2S)-5-carbamimidam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130055((S)-3-Cyano-N-[(S)-4-guanidino-1-(thiazole-2-carbo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed