Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50013408
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130312(4-[12-(4-Carboxy-4-{4-[(2,4-diamino-pteridin-6-ylm...)
Affinity DataKi:  0.0180nMAssay Description:Inhibitory constant for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130313(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  0.0330nMAssay Description:Inhibitory constant for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)
Affinity DataKi:  0.0420nMAssay Description:Inhibitory constant for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataKi:  0.0600nMAssay Description:Inhibitory constant for murine Wild-type dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)
Affinity DataKi:  0.810nMAssay Description:Inhibitory constant for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)
Affinity DataKi:  25.9nMAssay Description:Inhibitory constant for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130312(4-[12-(4-Carboxy-4-{4-[(2,4-diamino-pteridin-6-ylm...)
Affinity DataKi:  212nMAssay Description:Inhibitory constant for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50130313(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataKi:  333nMAssay Description:Inhibitory constant for F31A/F34A murine dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed