Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50013625
TargetAcetyl-CoA carboxylase 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132617(2-{1-[(E)-Ethoxyimino]-butyl}-3-hydroxy-5-(tetrahy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against rat heart ACC by the carboxylation of acetyl-CoA with [14C]-HCO3- to form [14C]-malonyl CoA; 18-40 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132616(2-{1-[(E)-(E)-3-Chloro-allyloxyimino]-propyl}-3-hy...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against rat heart ACC by the carboxylation of acetyl-CoA with [14C]-HCO3- to form [14C]-malonyl CoA; 18-40 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50075317(2-{1-[(E)-Ethoxyimino]-butyl}-5-(2-ethylsulfanyl-p...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against rat heart ACC by the carboxylation of acetyl-CoA with [14C]-HCO3- to form [14C]-malonyl CoA; 18-40 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132614(2-{1-[(E)-Ethoxyimino]-propyl}-3-hydroxy-5-(2,4,6-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against rat heart ACC by the carboxylation of acetyl-CoA with [14C]-HCO3- to form [14C]-malonyl CoA; 18-40 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132615(clethodim | 2-{1-[(E)-(E)-3-Chloro-allyloxyimino]-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against rat heart ACC by the carboxylation of acetyl-CoA with [14C]-HCO3- to form [14C]-malonyl CoA; 18-40 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50132618(3-{1-[(E)-Allyloxyimino]-butyl}-4-hydroxy-6,6-dime...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against rat heart ACC by the carboxylation of acetyl-CoA with [14C]-HCO3- to form [14C]-malonyl CoA; 18-40 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed