Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50013646
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132898(Dibutyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-p...)
Affinity DataKi:  0.620nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132907(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1-ethyl...)
Affinity DataKi:  1.70nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132901(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1,5-dim...)
Affinity DataKi:  1.70nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132892(Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...)
Affinity DataKi:  2nMAssay Description:Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132902(Dibutyl-[3-(2,4-dichloro-phenyl)-1-ethyl-5-methyl-...)
Affinity DataKi:  2.10nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132896([3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[...)
Affinity DataKi:  3.30nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132904(Butyl-[3-(2,4-dichloro-phenyl)-1-ethyl-5-methyl-1H...)
Affinity DataKi:  4.20nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132899([3-(2,4-Dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132901(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-1,5-dim...)
Affinity DataIC50: 5nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132894(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-2,5-dim...)
Affinity DataKi:  11nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132892(Butyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-pyr...)
Affinity DataIC50: 16nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132898(Dibutyl-[3-(2,4-dichloro-phenyl)-1,5-dimethyl-1H-p...)
Affinity DataIC50: 16nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132885(Dibutyl-[3-(2,4-dichloro-phenyl)-1-isopropyl-5-met...)
Affinity DataKi:  16nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132890(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-5-methy...)
Affinity DataKi:  26nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132887(Dibutyl-[2,5-dimethyl-3-(2,4,6-trimethyl-phenyl)-2...)
Affinity DataKi:  28nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132888(Butyl-[3-(2,4-dichloro-phenyl)-2-ethyl-5-methyl-2H...)
Affinity DataKi:  32nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132900([3-(2-Chloro-4-methyl-phenyl)-2-ethyl-5-methyl-2H-...)
Affinity DataKi:  32nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132889(Dibutyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-p...)
Affinity DataKi:  33nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132910(Dibutyl-[3-(2,4-dichloro-phenyl)-2-ethyl-5-methyl-...)
Affinity DataKi:  33nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132906(Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyr...)
Affinity DataKi:  35nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132905(Dibutyl-[3-(2,4-dichloro-phenyl)-2-isopropyl-5-met...)
Affinity DataKi:  37nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132893(Dibutyl-[3-(2,4-dichloro-phenyl)-5-methyl-1H-pyraz...)
Affinity DataKi:  40nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132895(Cyclopropylmethyl-[3-(2,4-dichloro-phenyl)-2-ethyl...)
Affinity DataKi:  46nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132911(Dibutyl-[3-(2-chloro-4-methyl-phenyl)-2-ethyl-5-me...)
Affinity DataKi:  59nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132886(Butyl-[3-(2,4-dichloro-phenyl)-5-methyl-1H-pyrazol...)
Affinity DataKi:  60nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132884(Dibutyl-[3-(2,4-dichloro-phenyl)-5-methyl-2-propyl...)
Affinity DataKi:  64nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132903(Dibutyl-[3-(2-chloro-4-methoxy-phenyl)-2,5-dimethy...)
Affinity DataKi:  70nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132897(Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyr...)
Affinity DataKi:  80nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132909([3-(4-Chloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-...)
Affinity DataKi:  82nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132908(Dibutyl-[3-(2,4-dichloro-phenyl)-5-methyl-1-propyl...)
Affinity DataKi:  180nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132891((2,5-Dimethyl-3-phenyl-2H-pyrazolo[4,3-b]pyridin-7...)
Affinity DataKi:  230nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132899([3-(2,4-Dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[...)
Affinity DataIC50: 365nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed