Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50036101
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000485(CHEMBL353196 | (S)-2-(5-chlorospiro[2,3-dihydroben...)
Affinity DataKi:  0.190nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000482(CHEMBL352411 | (R)-2-(5-chlorospiro[2,3-dihydroben...)
Affinity DataKi:  0.890nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000480(CHEMBL171867 | 2-(5-chlorospiro[2,3-dihydrobenzo[b...)
Affinity DataKi:  1.10nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000479(CHEMBL424950 | 7-Chloro-2,3,4,5-tetrahydro-benzo[b...)
Affinity DataKi:  1.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000492(ZACOPRIDE,R | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3...)
Affinity DataKi:  1.5nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000495(CHEMBL556193 | (ICS 205-930)1H-Indole-3-carboxylic...)
Affinity DataKi:  1.70nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000483(CHEMBL519643 | 1-Methyl-1H-indazole-3-carboxylic a...)
Affinity DataKi:  1.70nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000494(CHEMBL426935 | 7-Bromo-2,3,4,5-tetrahydro-benzo[b]...)
Affinity DataKi:  2.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000487(CHEMBL170278 | 8-Chloro-3,4,5,6-tetrahydro-2H-benz...)
Affinity DataKi:  4.70nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000489(CHEMBL353993 | N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-5-...)
Affinity DataKi:  6.10nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataKi:  6.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000478(CHEMBL170146 | 2,3,4,5-Tetrahydro-benzo[b]oxepine-...)
Affinity DataKi:  14nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000484(CHEMBL169443 | 7-Chloro-2,2-dimethyl-2,3,4,5-tetra...)
Affinity DataKi:  16nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000486(CHEMBL368992 | N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-2-...)
Affinity DataKi: >30nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000488(CHEMBL171070 | N-(1-Aza-bicyclo[2.2.2]oct-3-yl)-5-...)
Affinity DataKi:  47nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000490(CHEMBL173597 | 7-Chloro-2,3,4,5-tetrahydro-benzo[b...)
Affinity DataKi:  63nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50000481(CHEMBL353452 | 8-Amino-7-chloro-2,3,4,5-tetrahydro...)
Affinity DataKi: >100nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Rh£Ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataKi:  995nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed