Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50036013
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataIC50: 0.730nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50013388(CHEMBL350384 | BREMAZOCINE(-) | 6-Ethyl-3-(1-hydro...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000790(CHEMBL76023 | methyl 2-[4-cyclopropylmethyl-10,17-...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50013388(CHEMBL350384 | BREMAZOCINE(-) | 6-Ethyl-3-(1-hydro...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50013388(CHEMBL350384 | BREMAZOCINE(-) | 6-Ethyl-3-(1-hydro...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50013388(CHEMBL350384 | BREMAZOCINE(-) | 6-Ethyl-3-(1-hydro...)
Affinity DataIC50: 1.80nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000798(CHEMBL78932 | 4-cyclopropylmethyl-10-hydroxy-14-(4...)
Affinity DataIC50: 2.20nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001709(CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...)
Affinity DataIC50: 2.20nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50453225(CHEMBL2310843)
Affinity DataIC50: 2.30nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000790(CHEMBL76023 | methyl 2-[4-cyclopropylmethyl-10,17-...)
Affinity DataIC50: 2.5nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 2.80nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000793(CHEMBL311912 | 4-cyclopropylmethyl-14-(2-oxiranylm...)
Affinity DataIC50: 2.90nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000789(CHEMBL80531 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 3.40nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000797(CHEMBL80434 | 4-cyclopropylmethyl-14-(2-oxiranylme...)
Affinity DataIC50: 3.5nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000795(CHEMBL78796 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 4.20nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50453225(CHEMBL2310843)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000798(CHEMBL78932 | 4-cyclopropylmethyl-10-hydroxy-14-(4...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 8.90nMAssay Description:inhibition of 1.0 nM [3H]- DAGO binding to guinea pig brain membrane opioid receptor muMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000795(CHEMBL78796 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataIC50: 9.5nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000790(CHEMBL76023 | methyl 2-[4-cyclopropylmethyl-10,17-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000793(CHEMBL311912 | 4-cyclopropylmethyl-14-(2-oxiranylm...)
Affinity DataIC50: 11nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000797(CHEMBL80434 | 4-cyclopropylmethyl-14-(2-oxiranylme...)
Affinity DataIC50: 12nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000793(CHEMBL311912 | 4-cyclopropylmethyl-14-(2-oxiranylm...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50453225(CHEMBL2310843)
Affinity DataIC50: 12nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001709(CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000797(CHEMBL80434 | 4-cyclopropylmethyl-14-(2-oxiranylme...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 14nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000798(CHEMBL78932 | 4-cyclopropylmethyl-10-hydroxy-14-(4...)
Affinity DataIC50: 15nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM60212(SMR000058767 | NALTREXONE HYDROCHLORIDE | MLS00006...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000793(CHEMBL311912 | 4-cyclopropylmethyl-14-(2-oxiranylm...)
Affinity DataIC50: 17nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000797(CHEMBL80434 | 4-cyclopropylmethyl-14-(2-oxiranylme...)
Affinity DataIC50: 17nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000789(CHEMBL80531 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 18nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000789(CHEMBL80531 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000795(CHEMBL78796 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 19nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001709(CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...)
Affinity DataIC50: 20nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000790(CHEMBL76023 | methyl 2-[4-cyclopropylmethyl-10,17-...)
Affinity DataIC50: 21nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50001709(CHEMBL558140 | CHEMBL140278 | 4-cyclopropylmethyl-...)
Affinity DataIC50: 23nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000796(CHEMBL310785 | 4-cyclopropylmethyl-10-hydroxy-14-(...)
Affinity DataIC50: 25nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000789(CHEMBL80531 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 28nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50453225(CHEMBL2310843)
Affinity DataIC50: 34nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 43nMAssay Description:Inhibition of 0.5 nM [3H]bremazocine binding to guinea pig brain membrane opioid receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000795(CHEMBL78796 | 5-[4-cyclopropylmethyl-10,17-dihydro...)
Affinity DataIC50: 44nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000798(CHEMBL78932 | 4-cyclopropylmethyl-10-hydroxy-14-(4...)
Affinity DataIC50: 48nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 50nMAssay Description:Displacement of 0.5 nM [3H]bremazocine from guinea pig brain membrane opioid receptor kappa with 100 nM DAGO and 100 nM DPDPEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 62nMAssay Description:Inhibition of [3H]DPDPE binding to guinea pig brain membrane Opioid receptor delta 1 at 1.0 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed