Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50036046
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50001450(Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met NH2 | ...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002373(CHEMBL333069 | 1-(1-ethynyl)-15a,17a-dimethyl-(1R,...)
Affinity DataIC50: 24nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002373(CHEMBL333069 | 1-(1-ethynyl)-15a,17a-dimethyl-(1R,...)
Affinity DataIC50: 48nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002373(CHEMBL333069 | 1-(1-ethynyl)-15a,17a-dimethyl-(1R,...)
Affinity DataIC50: 50nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to standard Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002384(CHEMBL126009 | 15a,17a-dimethyl-1-vinyl-(1R,15aS,1...)
Affinity DataIC50: 86nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002390(CHEMBL124532 | 15a,17a-dimethyl-1-(1-propynyl)-(1R...)
Affinity DataIC50: 180nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002389(CHEMBL122020 | 1,15a,17a-trimethyl-(1S,15aS,17aS)-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002375(CHEMBL331346 | 15a,17a-dimethyl-(1S,15aS,17aS)-2,3...)
Affinity DataIC50: 220nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002378(CHEMBL331934 | 1-(1-ethynyl)-17a,19a-dimethyl-(1R,...)
Affinity DataIC50: 320nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002377(CHEMBL331978 | 15a,17a-dimethyl-1-(2-propynyl)-(1R...)
Affinity DataIC50: 320nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002382(CHEMBL3138259 | 1-(1-ethynyl)-1-hydroxy-16a,18a-di...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002394(CHEMBL340394 | 1-(1-ethynyl)-13a,15a-dimethyl-(1R,...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002396(methyl 4-[4,17-dihydroxy-15a,17a-dimethyl-(4R,15aS...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002391(CHEMBL126221 | 1-ethyl-15a,17a-dimethyl-(1S,15aS,1...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002385(CHEMBL122105 | 1-(1-ethynyl)-15a,17a-dimethyl-(1R,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002397(CHEMBL125428 | 2,4-dimethylbenzo[4,5]imidazo[1,2-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002395(CHEMBL121914 | 1-(1-ethynyl)-14a,16a-dimethyl-(1R,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002393(CHEMBL333776 | 11a-methyl-11-vinyl-(11aS)-7,7a,8,9...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002392(CHEMBL341283 | 1-(1,5-dimethylhexyl)-15a,17a-dimet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002388(CHEMBL122571 | 15a,17a-dimethyl-(15aS,17aS)-2,3,3a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002386(CHEMBL125493 | methyl 15a,17a-dimethyl-(1S,15aS,17...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002383(CHEMBL332279 | 15a,17a-dimethyl-1-phenyl-(1S,15aS,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002372(CHEMBL341271 | 1,2,3,4-tetrahydrobenzo[4,5]imidazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002381(CHEMBL338416 | 1-(1-ethynyl)-1-methoxy-15a,17a-dim...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002380(CHEMBL436581 | 15a,17a-dimethyl-(1S,15aS,17aS)-2,3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002379(CHEMBL331791 | 15a,17a-dimethyl-(15aS,17aS)-2,3,3a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Rat)
Rochester

Curated by ChEMBL
LigandPNGBDBM50002376(4-[4,17-dihydroxy-15a,17a-dimethyl-(4R,15aS,17S,17...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [125]I-Bolton Hunter Substance P([125]I-BHSP) binding to Tachykinin receptor 1 from rat forebrain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed