Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50036050
TargetNeutrophil elastase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003159(CHEMBL123153 | 3-(6-Hydroxy-2-methyl-5-oxo-2,5-dih...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Human Leukocyte ElastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003164(CHEMBL333759 | 1-[3-(6-Hydroxy-2-methyl-5-oxo-2,5-...)
Affinity DataKi:  250nMAssay Description:Inhibitory activity against HLE at 10 min (48 mM conc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003161(CHEMBL331287 | 3-Ethyl-7-methoxy-5,5,8-trioxo-5lam...)
Affinity DataKi:  500nMAssay Description:Second order rate constant for the in vitro inhibitory activity against human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50368407(L-658758 | CHEMBL446371)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibitory activity against HLE at 10 min (48 mM conc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406689(CHEMBL2114137)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibitory activity against HLE at 10 min (48 mM conc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003160(CHEMBL435611 | [(3-Acetoxymethyl-7-methoxy-5,5,8-t...)
Affinity DataKi:  6.10E+3nMAssay Description:Inhibitory activity against HLE at 10 min (48 mM conc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50003162(CHEMBL123475 | {[7-Methoxy-5,5,8-trioxo-3-(pyridin...)
Affinity DataKi:  4.30E+4nMAssay Description:Inhibitory activity against HLE at 10 min (48 mM conc)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed