Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50036069
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003845(CHEMBL136173 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 30nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003811(CHEMBL136063 | 2-(3-[1,3]Dioxan-2-yl-propylsulfany...)
Affinity DataIC50: 47nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50368461(CHEMBL1794871)
Affinity DataIC50: 64nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003829(CHEMBL136671 | 2-(3,3-Diethoxy-propylsulfanyl)-4,5...)
Affinity DataIC50: 69nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003846(CHEMBL442025 | 2-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 82nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003813(CHEMBL136167 | 2-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 90nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003808(CHEMBL344702 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 100nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003825(CHEMBL136338 | 2-Cyclohexylmethylsulfanyl-4,5-diph...)
Affinity DataIC50: 100nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003830(CHEMBL336696 | 6-[4,5-Bis-(3-chloro-phenyl)-1H-imi...)
Affinity DataIC50: 110nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003838(CHEMBL137147 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 140nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003818(CHEMBL337736 | 6-[4,5-Bis-(2-chloro-phenyl)-1H-imi...)
Affinity DataIC50: 140nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003839(CHEMBL136503 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 160nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003842(CHEMBL345058 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 170nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50368458(CHEMBL1794872)
Affinity DataIC50: 170nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003814(CHEMBL140292 | 2-([1,3]Dioxan-2-ylmethylsulfanyl)-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003847(CHEMBL136489 | 6-[4,5-Bis-(4-chloro-phenyl)-1H-imi...)
Affinity DataIC50: 180nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003834(CHEMBL135084 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 200nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003836(CHEMBL335107 | 4,5-Diphenyl-2-(tetrahydro-pyran-2-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50368459(CHEMBL1794875)
Affinity DataIC50: 230nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003817(CHEMBL136113 | 6-[4,5-Bis-(4-chloro-phenyl)-1H-imi...)
Affinity DataIC50: 250nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003820(CHEMBL136625 | 2-(2,2-Diethoxy-ethylsulfanyl)-4,5-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003826(CHEMBL342030 | 2-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 280nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003837(CHEMBL136540 | 6-(4,5-Di-p-tolyl-1H-imidazol-2-yls...)
Affinity DataIC50: 280nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003806(CHEMBL136286 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 280nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003805(CHEMBL136105 | 2-Benzylsulfanyl-4,5-diphenyl-1H-im...)
Affinity DataIC50: 290nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003809(CHEMBL435986 | 6-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Affinity DataIC50: 340nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003832(CHEMBL138948 | 5-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 360nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003821(CHEMBL337377 | 6-[4,5-Bis-(4-methoxy-phenyl)-1H-im...)
Affinity DataIC50: 420nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003841(CHEMBL335574 | 6-[4,5-Bis-(3-chloro-phenyl)-1H-imi...)
Affinity DataIC50: 440nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003816(CHEMBL136675 | 2-([1,3]Dioxolan-2-ylmethylsulfanyl...)
Affinity DataIC50: 530nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003831(CHEMBL139212 | 4-(3-Chloro-phenyl)-5-phenyl-2-(tet...)
Affinity DataIC50: 560nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003824(CHEMBL423351 | 6-[4,5-Bis-(3-methoxy-phenyl)-1H-im...)
Affinity DataIC50: 570nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003822(CHEMBL337308 | 2-(2,2-Dimethoxy-ethylsulfanyl)-4,5...)
Affinity DataIC50: 580nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003828(CHEMBL337107 | 6-[4,5-Bis-(4-fluoro-phenyl)-1H-imi...)
Affinity DataIC50: 610nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003810(CHEMBL342177 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 610nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003833(CHEMBL140291 | 2-(2-[1,3]Dioxan-2-yl-ethylsulfanyl...)
Affinity DataIC50: 730nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003844(CHEMBL136745 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 740nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003840(CHEMBL274020 | 2-Ethylsulfanyl-4,5-diphenyl-1H-imi...)
Affinity DataIC50: 770nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003823(CHEMBL342040 | 6-[4,5-Bis-(4-fluoro-phenyl)-1H-imi...)
Affinity DataIC50: 790nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003843(CHEMBL422099 | 6-(4,5-Diphenyl-1H-imidazol-2-ylsul...)
Affinity DataIC50: 910nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50368460(CHEMBL1794869)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003827(CHEMBL139412 | 6-[4,5-Bis-(2-chloro-phenyl)-1H-imi...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Rat)
Rhone-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50368462(CHEMBL1794870)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2012
Entry Details Article
PubMed