Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50013723
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50122654(sufugolix | TAK-013 | 1-{4-[5-[(Benzyl-methyl-amin...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50067485(CHEMBL544440 | 3-[(Benzyl-methyl-amino)-methyl]-7-...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133856(1-(2,6-Difluoro-benzyl)-5-{[methyl-(2-pyridin-2-yl...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50122657(N-{4-[5-[(benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50122674(N-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50098391(4-(2-Azetidin-2-yl-ethoxy)-7-chloro-2-oxo-3-(3,4,5...)
Affinity DataKi:  4nMAssay Description:Binding affinity towards rat Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133849(N-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133839(1-(2,6-Difluoro-benzyl)-5-[(methyl-pyridin-2-ylmet...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133843(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133844(N-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133847(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133840(1-(2,6-difluorobenzyl)-6-(4-aminophenyl)-5-((benzy...)
Affinity DataKi:  36nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133854((S)-2-Amino-N-{4-[5-[(benzyl-methyl-amino)-methyl]...)
Affinity DataKi:  43nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133842((R)-2-Amino-4-methyl-pentanoic acid {4-[5-[(benzyl...)
Affinity DataKi:  58nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50067485(CHEMBL544440 | 3-[(Benzyl-methyl-amino)-methyl]-7-...)
Affinity DataKi:  60nMAssay Description:Binding affinity towards rat Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133845(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)
Affinity DataKi:  61nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133857(5-{[(2-Diethylamino-ethyl)-methyl-amino]-methyl}-1...)
Affinity DataKi:  76nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133855(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)
Affinity DataKi:  88nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133859(2-Amino-N-{4-[5-[(benzyl-methyl-amino)-methyl]-1-(...)
Affinity DataKi:  150nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133851(1-(2,6-Difluoro-benzyl)-5-{[(2-methoxy-ethyl)-meth...)
Affinity DataKi:  170nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133848(1-(2,6-difluorobenzyl)-5-((methyl(phenethyl)amino)...)
Affinity DataKi:  170nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133841(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133858(5-[(Butyl-methyl-amino)-methyl]-1-(2,6-difluoro-be...)
Affinity DataKi:  270nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133850(4-Amino-N-{4-[5-[(benzyl-methyl-amino)-methyl]-1-(...)
Affinity DataKi:  300nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133853(3-Amino-N-{4-[5-[(benzyl-methyl-amino)-methyl]-1-(...)
Affinity DataKi:  360nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133852(1-(2,6-Difluoro-benzyl)-6-(4-nitro-phenyl)-3-pheny...)
Affinity DataKi:  460nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50133846(1-(2,6-Difluoro-benzyl)-5-dimethylaminomethyl-6-(4...)
Affinity DataKi:  640nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed