Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 863
LigandPNGBDBM6760(CHEMBL281948 | methyl (15S,16R,18R)-16-hydroxy-15-...)
Affinity DataIC50: 30nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6772(3-[3-(methylamino)propyl]-3,13,23-triazahexacyclo[...)
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6781(3-(2,3-dihydroxypropyl)-23-methyl-3,13,23-triazahe...)
Affinity DataIC50: 60nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6770(3-(3-hydroxypropyl)-3,13,23-triazahexacyclo[14.7.0...)
Affinity DataIC50: 70nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6776(3-methyl-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0...)
Affinity DataIC50: 80nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6768(indolocarbazole deriv. 4(f) | 20-bromo-3-methyl-3,...)
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6766(indolocarbazole deriv. 4(h) | 20-fluoro-3-methyl-3...)
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6772(3-[3-(methylamino)propyl]-3,13,23-triazahexacyclo[...)
Affinity DataIC50: 120nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2684(indolocarbazole deriv. 4f | 3-[3-(dimethylamino)pr...)
Affinity DataIC50: 130nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2672(6,7,12,13-Tetrahydro-5,7-dioxo-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: 140nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6766(indolocarbazole deriv. 4(h) | 20-fluoro-3-methyl-3...)
Affinity DataIC50: 140nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6772(3-[3-(methylamino)propyl]-3,13,23-triazahexacyclo[...)
Affinity DataIC50: 160nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6778(6,20-dimethoxy-3,13,23-triazahexacyclo[14.7.0.0^{2...)
Affinity DataIC50: 180nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6770(3-(3-hydroxypropyl)-3,13,23-triazahexacyclo[14.7.0...)
Affinity DataIC50: 180nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6781(3-(2,3-dihydroxypropyl)-23-methyl-3,13,23-triazahe...)
Affinity DataIC50: 260nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6760(CHEMBL281948 | methyl (15S,16R,18R)-16-hydroxy-15-...)
Affinity DataIC50: 260nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6763(28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0...)
Affinity DataIC50: 540nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2591(3,4-bis(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyr...)
Affinity DataIC50: 580nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6763(28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0...)
Affinity DataIC50: 680nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6767(3-(6-bromo-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-y...)
Affinity DataIC50: 730nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6781(3-(2,3-dihydroxypropyl)-23-methyl-3,13,23-triazahe...)
Affinity DataIC50: 810nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2581(CHEMBL16958 | 3,13,23-triazahexacyclo[14.7.0.0^{2,...)
Affinity DataIC50: 830nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6765(3-(6-fluoro-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 840nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2591(3,4-bis(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyr...)
Affinity DataIC50: 890nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2672(6,7,12,13-Tetrahydro-5,7-dioxo-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: 900nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6771(3-(1H-indol-3-yl)-4-{1-[3-(methylamino)propyl]-1H-...)
Affinity DataIC50: 960nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50: 990nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6769(3-[1-(3-hydroxypropyl)-1H-indol-3-yl]-4-(1H-indol-...)
Affinity DataIC50: 1.17E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2590(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)
Affinity DataIC50: 1.25E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6765(3-(6-fluoro-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6780(3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...)
Affinity DataIC50: 1.61E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6767(3-(6-bromo-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-y...)
Affinity DataIC50: 1.88E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2590(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)
Affinity DataIC50: 1.95E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6780(3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...)
Affinity DataIC50: 2.14E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2684(indolocarbazole deriv. 4f | 3-[3-(dimethylamino)pr...)
Affinity DataIC50: 2.20E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6771(3-(1H-indol-3-yl)-4-{1-[3-(methylamino)propyl]-1H-...)
Affinity DataIC50: 3.52E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6777(3,4-bis(6-methoxy-1H-indol-3-yl)-2,5-dihydro-1H-py...)
Affinity DataIC50: 4.64E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2583(bis-indolylmaleimide deriv. 8a | 3,4-bis(1H-indol-...)
Affinity DataIC50: 5.81E+3nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2683(2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)
Affinity DataIC50: 1.02E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2590(bis-indolylmaleimide deriv. 8g | 3-(1H-indol-3-yl)...)
Affinity DataIC50: 1.17E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2583(bis-indolylmaleimide deriv. 8a | 3,4-bis(1H-indol-...)
Affinity DataIC50: 1.17E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6769(3-[1-(3-hydroxypropyl)-1H-indol-3-yl]-4-(1H-indol-...)
Affinity DataIC50: 1.47E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6765(3-(6-fluoro-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 1.62E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6776(3-methyl-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6778(6,20-dimethoxy-3,13,23-triazahexacyclo[14.7.0.0^{2...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2591(3,4-bis(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyr...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6780(3-[1-(2,3-dihydroxypropyl)-1H-indol-3-yl]-4-(1-met...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2583(bis-indolylmaleimide deriv. 8a | 3,4-bis(1H-indol-...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM2672(6,7,12,13-Tetrahydro-5,7-dioxo-5H-indolo[2,3-a]pyr...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6766(indolocarbazole deriv. 4(h) | 20-fluoro-3-methyl-3...)
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
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