Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 1980
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15774((2R)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15773((2S)-1-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]py...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15776(2-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15775(1-{4-[3-(4-Fluoro-phenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15772(4-({4-[3-(4-fluorophenyl)-1H-pyrrolo[3,2-b]pyridin...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15756(3-(4-Fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[3,2...)
Affinity DataIC50: 6.5nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15764(4-[3-(4-fluorophenyl)-1-(1-methoxyethyl)-1H-pyrrol...)
Affinity DataIC50: 21nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15765(3-(4-Fluorophenyl)-1-ethyl-2-pyridin-4-yl-1H-pyrro...)
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15759(4-[7-(4-fluorophenyl)-5H-pyrrolo[2,3-b]pyrazin-6-y...)
Affinity DataIC50: 53nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15763(3-(4-Fluoro-phenyl)-1-methoxy-2-pyridin-4-yl-1H-py...)
Affinity DataIC50: 68nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15762(4-[3-(4-fluorophenyl)furo[3,2-b]pyridin-2-yl]pyrid...)
Affinity DataIC50: 86nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15766(3-(4-Fluorophenyl)-1-methyl-2-pyridin-4-yl-1H-pyrr...)
Affinity DataIC50: 98nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15767(1-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[...)
Affinity DataIC50: 172nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15768(4-{1-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrro...)
Affinity DataIC50: 185nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15769(4-[3-(4-fluorophenyl)-1-[1-(pyrrolidin-1-yl)ethyl]...)
Affinity DataIC50: 217nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15760(7-(4-Fluorophenyl)-6-pyridin-4-yl-5H-pyrrolo[3,2-d...)
Affinity DataIC50: 895nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15758(3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-indole | 3-...)
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15770(4-[3-(4-fluorophenyl)-1-[1-(piperidin-1-yl)ethyl]-...)
Affinity DataIC50: 1.97E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15757(3-(4-Fluorophenyl)-2-pyridin-4-yl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 3.10E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15761(7-(4-Fluoro-phenyl)-6-pyridin-4-yl-7H-pyrrolo[2,3-...)
Affinity DataIC50: 3.30E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

LigandPNGBDBM15771(2-[3-(4-fluorophenyl)-2-(pyridin-4-yl)-1H-pyrrolo[...)
Affinity DataIC50: 2.36E+4nMpH: 7.4 T: 2°CAssay Description:Inhibition of human recombinant active p38alpha MAP kinase was tested by measuring the incorporation of 33P from gamma-[33P] ATP into myelin basic pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed