Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50013804
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: 4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50090528(Ro-04-6790 | 4-Amino-N-(2,6-bis-dimethylamino-pyri...)
Affinity DataIC50: 26.3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134811(3-Benzenesulfonyl-2-methylsulfanyl-pyrimido[2,1-a]...)
Affinity DataIC50: 68.9nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134812(3-Benzenesulfonyl-8-ethyl-2-methylsulfanyl-pyrido[...)
Affinity DataIC50: 70.1nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134809(2-Methylsulfanyl-3-(naphthalene-2-sulfonyl)-pyrido...)
Affinity DataIC50: 79.2nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134810(3-Benzenesulfonyl-7-fluoro-2-methylsulfanyl-pyrido...)
Affinity DataIC50: 87.6nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134808(3-Benzenesulfonyl-9-bromo-7-methyl-2-methylsulfany...)
Affinity DataIC50: 269nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134806((E)-2-Benzenesulfonyl-3-(pyridin-2-ylamino)-acrylo...)
Affinity DataIC50: 524nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant human Cytochrome P450 19A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134813(2-Methylsulfanyl-3-(propane-1-sulfonyl)-pyrido[1,2...)
Affinity DataIC50: 3.58E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 6 receptor using [3H]- LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 3A4 with BzResMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50134807(3-Benzenesulfonyl-2-methylsulfanyl-pyrido[1,2-a]py...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human Cytochrome P450 3A4 with BFCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed