Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 1764
LigandPNGBDBM13988(1:1 racemic mixture | 2-(carboxymethoxy)-5-[2-acet...)
Affinity DataKi:  2.20E+3nM ΔG°:  -32.0kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13978(1:1 racemic mixture | ({4-[2-acetamido-2-({4-[3-hy...)
Affinity DataKi:  6.10E+3nM ΔG°:  -29.5kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13977(({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-({4-[...)
Affinity DataKi:  8.80E+3nM ΔG°:  -28.6kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13987(2-{4-[2-acetamido-2-({4-[3-hydroxy-2-(methoxycarbo...)
Affinity DataKi:  9.00E+3nM ΔG°:  -28.5kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM13976(CHEMBL116605 | Aminobenzoic acid analog 5)
Affinity DataKi:  1.80E+4nM ΔG°:  -26.8kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13976(CHEMBL116605 | Aminobenzoic acid analog 5)
Affinity DataKi:  6.50E+4nM ΔG°:  -23.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13977(({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-({4-[...)
Affinity DataKi:  1.41E+5nM ΔG°:  -21.8kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13987(2-{4-[2-acetamido-2-({4-[3-hydroxy-2-(methoxycarbo...)
Affinity DataKi:  1.82E+5nM ΔG°:  -21.1kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13984((2Z)-3-{4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13985(2-{4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-({4-...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13983(2-({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-({4...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13982(1:1 racemic mixture | methyl 2-[4-(2-acetamido-3-{...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13989(2-{2-amino-4-[2-acetamido-2-({4-[3-hydroxy-2-(meth...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13981(1:1 racemic mixture | methyl 2-(4-{2-acetamido-3-[...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13980(1:1 racemic mixture | methyl 2-(4-{2-acetamido-3-[...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Abbott Laboratories

LigandPNGBDBM13986(CHEMBL106109 | 2-{4-[(2S)-2-{[(tert-butoxy)carbony...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13979(1:1 racemic mixture | methyl 2-(4-{2-acetamido-3-[...)
Affinity DataKi: >2.00E+5nM ΔG°: >-20.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
LigandPNGBDBM13986(CHEMBL106109 | 2-{4-[(2S)-2-{[(tert-butoxy)carbony...)
Affinity DataKi:  2.20E+5nM ΔG°:  -20.7kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed