Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50013875
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135635(2-[2-(Isothiazole-3-carbonyl)-pyrrolidine-1-carbon...)
Affinity DataKi:  0.260nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135633((S)-benzyl 2-((S)-2-(5-(benzyloxymethyl)isoxazole-...)
Affinity DataKi:  0.280nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135637(1-{(S)-2-[(S)-2-(5-Benzyloxymethyl-isoxazole-3-car...)
Affinity DataKi:  0.340nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135634((S)-2-[(S)-2-(5-Trimethylsilanyl-isoxazole-3-carbo...)
Affinity DataKi:  0.450nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)
Affinity DataKi:  1.87nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)
Affinity DataKi:  1.90nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135633((S)-benzyl 2-((S)-2-(5-(benzyloxymethyl)isoxazole-...)
Affinity DataKi:  3.30nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135633((S)-benzyl 2-((S)-2-(5-(benzyloxymethyl)isoxazole-...)
Affinity DataKi:  3.30nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135633((S)-benzyl 2-((S)-2-(5-(benzyloxymethyl)isoxazole-...)
Affinity DataKi:  4nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135633((S)-benzyl 2-((S)-2-(5-(benzyloxymethyl)isoxazole-...)
Affinity DataKi:  4nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135636((S)-2-[(S)-2-(5-Cyano-isoxazole-3-carbonyl)-pyrrol...)
Affinity DataKi:  7.5nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)
Affinity DataKi:  15nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135630((S)-2-[(S)-2-(5-Phenyl-isoxazole-3-carbonyl)-pyrro...)
Affinity DataKi:  15nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135635(2-[2-(Isothiazole-3-carbonyl)-pyrrolidine-1-carbon...)
Affinity DataKi:  16nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135634((S)-2-[(S)-2-(5-Trimethylsilanyl-isoxazole-3-carbo...)
Affinity DataKi:  19nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135632((S)-2-[(S)-2-(Isoxazole-3-carbonyl)-pyrrolidine-1-...)
Affinity DataKi:  36nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135636((S)-2-[(S)-2-(5-Cyano-isoxazole-3-carbonyl)-pyrrol...)
Affinity DataKi:  38nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135632((S)-2-[(S)-2-(Isoxazole-3-carbonyl)-pyrrolidine-1-...)
Affinity DataKi:  72nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135631(3-[(S)-1-((S)-1-Benzyloxycarbonyl-pyrrolidine-2-ca...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruzi; Moderately activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135631(3-[(S)-1-((S)-1-Benzyloxycarbonyl-pyrrolidine-2-ca...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed