Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50013922
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092509((S)-3-{4-[2-(6-Amino-pyridin-2-yl)-ethyl]-benzoyla...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135967(2-((S)-(1R,7S)-7,7-Dimethyl-2-oxo-bicyclo[2.2.1]he...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083763([(S)-8-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-3-o...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107397(3-(2-{(S)-2-Oxo-3-[2-(5,6,7,8-tetrahydro-[1,8]naph...)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135968(3-Pyrimidin-5-yl-3-(5-5,6,7,8-tetrahydro-[1,8]naph...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076058(2-((S)-Benzenesulfonylamino)-3-(4-piperazin-1-yl-b...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135967(2-((S)-(1R,7S)-7,7-Dimethyl-2-oxo-bicyclo[2.2.1]he...)
Affinity DataIC50: 157nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091737(2-Benzenesulfonylamino-3-[4-(2-piperidin-4-yl-etho...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50004058(N-(butylsulfonyl)-O-(4-piperidin-4-ylbutyl)-L-tyro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076058(2-((S)-Benzenesulfonylamino)-3-(4-piperazin-1-yl-b...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092509((S)-3-{4-[2-(6-Amino-pyridin-2-yl)-ethyl]-benzoyla...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107397(3-(2-{(S)-2-Oxo-3-[2-(5,6,7,8-tetrahydro-[1,8]naph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107402(2-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135968(3-Pyrimidin-5-yl-3-(5-5,6,7,8-tetrahydro-[1,8]naph...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107402(2-[2-(2-Amino-5-guanidino-pentanoylamino)-acetylam...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of binding to human Vitronectin receptor (integrin alphaV-beta3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50083763([(S)-8-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-3-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alphaIIb-beta3 integrin in platelet aggregation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed