Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50014130
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138530((2R,3S,4R)-2-Hydroxymethyl-5-{6-[(R)-(tetrahydro-f...)
Affinity DataKi:  3nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138535(Benzyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydroxy-...)
Affinity DataKi:  12nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138525(Ethyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydroxy-5...)
Affinity DataKi:  33nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138524(Allyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydroxy-5...)
Affinity DataKi:  35nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138540(Isopropyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydro...)
Affinity DataKi:  36nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138527(Methyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydroxy-...)
Affinity DataKi:  45nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138534(Propyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydroxy-...)
Affinity DataKi:  50nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138541(Ethyl-thiocarbamic acid (2R,3S,4R)-5-{2-chloro-6-[...)
Affinity DataKi:  55nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138545(2-(6-Cyclopentylamino-purin-9-yl)-5-methyl-tetrahy...)
Affinity DataKi:  70nMAssay Description:Binding affinity against rat Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138536(Methyl-thiocarbamic acid (2R,3S,4R)-5-{2-chloro-6-...)
Affinity DataKi:  71nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138544(Cyclopentyl-thiocarbamic acid (2R,3S,4R)-3,4-dihyd...)
Affinity DataKi:  72nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138547(Isopropyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-5...)
Affinity DataKi:  78nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138521(Methyl-carbamic acid (2R,3S,4R)-5-{2-chloro-6-[(R)...)
Affinity DataKi:  96nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138533(Methyl-carbamic acid (2R,3R,5R)-3,4-dihydroxy-5-{6...)
Affinity DataKi:  140nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138543(Cyclobutyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydr...)
Affinity DataKi:  148nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138532(Cyclopropyl-thiocarbamic acid (2R,3S,4R)-3,4-dihyd...)
Affinity DataKi:  157nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138537(Butyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydroxy-5...)
Affinity DataKi:  157nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138548(Ethyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-5-{6-...)
Affinity DataKi:  167nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138542(Dimethyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydrox...)
Affinity DataKi:  205nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138551(Cyclopropyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy...)
Affinity DataKi:  209nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138523(Cyclopentyl-carbamic acid (2R,3S,4R)-5-{2-chloro-6...)
Affinity DataKi:  226nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138546(Propyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-5-{6...)
Affinity DataKi:  235nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138550(Dimethyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-5-...)
Affinity DataKi:  238nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138529(Cyclohexyl-thiocarbamic acid (2R,3S,4R)-3,4-dihydr...)
Affinity DataKi:  253nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138549(Cyclobutyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-...)
Affinity DataKi:  306nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138531(Cyclopentyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy...)
Affinity DataKi:  321nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138526(Allyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-5-{6-...)
Affinity DataKi:  524nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138538(Cyclohexyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-...)
Affinity DataKi:  584nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138522(Butyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-5-{6-...)
Affinity DataKi:  1.41E+3nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138539(Benzyl-carbamic acid (2R,3S,4R)-3,4-dihydroxy-5-{6...)
Affinity DataKi:  1.83E+3nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50138528((4-Fluoro-benzyl)-carbamic acid (2R,3S,4R)-3,4-dih...)
Affinity DataKi:  1.91E+3nMAssay Description:Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed