Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 2648
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22920(1-[(2R)-1-hydroxy-4-{6-[3-(1-methyl-1H-1,3-benzodi...)
Affinity DataKi:  7.70nM ΔG°:  -45.8kJ/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22919(CHEMBL327830 | imidazole-4-carboxamide derivative,...)
Affinity DataKi:  680nM ΔG°:  -34.8kJ/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22918(2-(4-{5-[(1H-1,3-benzodiazol-2-ylamino)methyl]thio...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetAdenosine deaminase(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM22917(1-(1-hydroxy-4-phenylbutan-2-yl)-1H-imidazole-4-ca...)
Affinity DataKi:  5.90E+3nM ΔG°:  -29.5kJ/molepH: 7.4 T: 2°CAssay Description:The reaction velocity was measured by change in absorbance at 265nm (A265) resulting from the deamination of adenosine. The reaction was started by a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)