Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 2607
TargetHistamine H4 receptor(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  4.10nM ΔG°:  -47.9kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  4.60nM ΔG°:  -47.6kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  4.70E+3nM ΔG°:  -30.4kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  5.13E+3nM ΔG°:  -30.2kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H1 receptor(Mouse)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed