Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50014219
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139695(3-((S)-2-{(S)-2-[2-((S)-Acetylamino)-3-(4-hydroxy-...)
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139699(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-carboxy-b...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091585(3-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propio...)
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139702(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139690(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataIC50: 976nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139701(3-Benzyloxycarbonylamino-5-(2-naphthalen-1-yl-etha...)
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139698(3-Benzyloxycarbonylamino-4-oxo-5-(2-phenyl-ethanes...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139697(3-Benzyloxycarbonylamino-5-(2-cyclohexyl-ethanesul...)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139700(3-Benzyloxycarbonylamino-4-oxo-5-phenylmethanesulf...)
Affinity DataIC50: 1.68E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139694(3-Benzyloxycarbonylamino-5-(naphthalene-1-sulfonyl...)
Affinity DataIC50: 1.74E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139703(3-Benzyloxycarbonylamino-5-(indan-1-ylmethanesulfo...)
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139693(3-Benzyloxycarbonylamino-4-oxo-5-(3-phenyl-propane...)
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139691(5-Benzenesulfonylamino-3-benzyloxycarbonylamino-4-...)
Affinity DataIC50: 2.91E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139696(3-Benzyloxycarbonylamino-4-oxo-9-phenyl-nonanoic a...)
Affinity DataIC50: 1.03E+6nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139692(3-Benzyloxycarbonylamino-5-methanesulfonylamino-4-...)
Affinity DataIC50: 1.83E+6nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139702(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139695(3-((S)-2-{(S)-2-[2-((S)-Acetylamino)-3-(4-hydroxy-...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091585(3-(2-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propio...)
Affinity DataKi:  14nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139699(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-4-carboxy-b...)
Affinity DataKi:  24nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139690(3-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-methyl-bu...)
Affinity DataKi:  134nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139698(3-Benzyloxycarbonylamino-4-oxo-5-(2-phenyl-ethanes...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139701(3-Benzyloxycarbonylamino-5-(2-naphthalen-1-yl-etha...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139694(3-Benzyloxycarbonylamino-5-(naphthalene-1-sulfonyl...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139697(3-Benzyloxycarbonylamino-5-(2-cyclohexyl-ethanesul...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139693(3-Benzyloxycarbonylamino-4-oxo-5-(3-phenyl-propane...)
Affinity DataKi:  3.45E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139691(5-Benzenesulfonylamino-3-benzyloxycarbonylamino-4-...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139703(3-Benzyloxycarbonylamino-5-(indan-1-ylmethanesulfo...)
Affinity DataKi:  6.50E+4nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139696(3-Benzyloxycarbonylamino-4-oxo-9-phenyl-nonanoic a...)
Affinity DataKi:  1.19E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50139692(3-Benzyloxycarbonylamino-5-methanesulfonylamino-4-...)
Affinity DataKi:  7.35E+5nMAssay Description:Inhibitory activity against caspase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed