Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50014424
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142577(11-(4-Chloro-phenyl)-9-(4-methyl-thiazol-2-yl)-6,7...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]Ro-151788 from human GABA-A receptor alpha-1-beta-3-gamma-2 subunits expressed in L(tk) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142567(9-(4-Methyl-thiazol-2-yl)-11-phenyl-6,7-dihydro-5H...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]Ro-151788 from human GABA-A receptor alpha2 subunit expressed in L(tk) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142567(9-(4-Methyl-thiazol-2-yl)-11-phenyl-6,7-dihydro-5H...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142577(11-(4-Chloro-phenyl)-9-(4-methyl-thiazol-2-yl)-6,7...)
Affinity DataKi:  0.400nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142570(9-(4-Methyl-thiazol-2-yl)-11-pyridin-4-yl-6,7-dihy...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142567(9-(4-Methyl-thiazol-2-yl)-11-phenyl-6,7-dihydro-5H...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142563(9-(4-Methyl-thiazol-2-yl)-11-o-tolyl-6,7-dihydro-5...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142570(9-(4-Methyl-thiazol-2-yl)-11-pyridin-4-yl-6,7-dihy...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142563(9-(4-Methyl-thiazol-2-yl)-11-o-tolyl-6,7-dihydro-5...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142565(9-(4-Methyl-thiazol-2-yl)-11-pyridin-3-yl-6,7-dihy...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142569(11-(2-Fluoro-phenyl)-9-(4-methyl-thiazol-2-yl)-6,7...)
Affinity DataKi:  3nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142562(11-(1-Methyl-1H-pyrrol-2-yl)-9-(4-methyl-thiazol-2...)
Affinity DataKi:  3nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142561(11-(3,5-Dimethyl-isoxazol-4-yl)-9-(4-methyl-thiazo...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142566(4-[9-(4-Methyl-thiazol-2-yl)-8-oxo-5,6,7,8-tetrahy...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142571(11-Furan-3-yl-9-(4-methyl-thiazol-2-yl)-6,7-dihydr...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142562(11-(1-Methyl-1H-pyrrol-2-yl)-9-(4-methyl-thiazol-2...)
Affinity DataKi:  4nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142578(9-(4-Methyl-thiazol-2-yl)-11-(1H-pyrrol-2-yl)-6,7-...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142571(11-Furan-3-yl-9-(4-methyl-thiazol-2-yl)-6,7-dihydr...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142561(11-(3,5-Dimethyl-isoxazol-4-yl)-9-(4-methyl-thiazo...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142568(9-(4-Methyl-thiazol-2-yl)-11-pyridazin-4-yl-6,7-di...)
Affinity DataKi:  5nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142569(11-(2-Fluoro-phenyl)-9-(4-methyl-thiazol-2-yl)-6,7...)
Affinity DataKi:  5nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142565(9-(4-Methyl-thiazol-2-yl)-11-pyridin-3-yl-6,7-dihy...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142566(4-[9-(4-Methyl-thiazol-2-yl)-8-oxo-5,6,7,8-tetrahy...)
Affinity DataKi:  5.40nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142578(9-(4-Methyl-thiazol-2-yl)-11-(1H-pyrrol-2-yl)-6,7-...)
Affinity DataKi:  7.80nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142568(9-(4-Methyl-thiazol-2-yl)-11-pyridazin-4-yl-6,7-di...)
Affinity DataKi:  8.30nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142579(9-(4-Methyl-thiazol-2-yl)-11-pyrimidin-4-yl-6,7-di...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142574(9-(4-Methyl-thiazol-2-yl)-11-pyrimidin-5-yl-6,7-di...)
Affinity DataKi:  9nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142575(11-(1-Methyl-1H-pyrazol-3-yl)-9-(4-methyl-thiazol-...)
Affinity DataKi:  10nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142579(9-(4-Methyl-thiazol-2-yl)-11-pyrimidin-4-yl-6,7-di...)
Affinity DataKi:  12nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142564(11-(1-Methyl-1H-imidazol-2-yl)-9-(4-methyl-thiazol...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]Ro-151788 from human GABA-A receptor alpha-1-beta-3-gamma-2 subunits expressed in L(tk) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142573(9-(4-Methyl-thiazol-2-yl)-11-pyridazin-3-yl-6,7-di...)
Affinity DataKi:  17nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142564(11-(1-Methyl-1H-imidazol-2-yl)-9-(4-methyl-thiazol...)
Affinity DataKi:  17nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142575(11-(1-Methyl-1H-pyrazol-3-yl)-9-(4-methyl-thiazol-...)
Affinity DataKi:  20nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142574(9-(4-Methyl-thiazol-2-yl)-11-pyrimidin-5-yl-6,7-di...)
Affinity DataKi:  21nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142573(9-(4-Methyl-thiazol-2-yl)-11-pyridazin-3-yl-6,7-di...)
Affinity DataKi:  26nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142570(9-(4-Methyl-thiazol-2-yl)-11-pyridin-4-yl-6,7-dihy...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]Ro-151788 from human GABA-A receptor alpha4 subunit expressed in L(tk) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142576(11-(4-tert-Butyl-phenyl)-9-(4-methyl-thiazol-2-yl)...)
Affinity DataKi: >33nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142572(9-(4-Methyl-thiazol-2-yl)-11-naphthalen-2-yl-6,7-d...)
Affinity DataKi: >33nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-3-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142570(9-(4-Methyl-thiazol-2-yl)-11-pyridin-4-yl-6,7-dihy...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-Ro-15-1788 from human GABA-A receptor alpha5 subunit expressed in L(tk) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142572(9-(4-Methyl-thiazol-2-yl)-11-naphthalen-2-yl-6,7-d...)
Affinity DataKi: >33nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142576(11-(4-tert-Butyl-phenyl)-9-(4-methyl-thiazol-2-yl)...)
Affinity DataKi: >33nMAssay Description:Binding affinity at human recombinant gamma-aminobutyric-acid A receptor alpha-1-beta-3-gamma-2 expressed in L(tk) cells by [3H]Ro-151788 displacemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(Human)
The Neuroscience Research Centre

Curated by ChEMBL
LigandPNGBDBM50142570(9-(4-Methyl-thiazol-2-yl)-11-pyridin-4-yl-6,7-dihy...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]Ro-151788 from human GABA-A receptor alpha6 subunit expressed in L(tk) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed