Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50014425
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142589(N-{4-[2-(4-Chloro-phenyl)-5-trifluoromethyl-2H-pyr...)
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 36nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 67nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142592(N-{4-[2-(4-Bromo-phenyl)-5-trifluoromethyl-2H-pyra...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142582(4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyraz...)
Affinity DataIC50: 72nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142582(4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyraz...)
Affinity DataIC50: 129nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142583(N-{4-[2-(4-Chloro-phenyl)-5-difluoromethyl-2H-pyra...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142591(N-{4-[2-(4-Bromo-phenyl)-5-trifluoromethyl-2H-pyra...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142587(N-{4-[2-(4-Chloro-phenyl)-5-methyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 265nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142586(N-{4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-py...)
Affinity DataIC50: 400nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142580(N-{4-[2-(4-Dimethylamino-phenyl)-5-trifluoromethyl...)
Affinity DataIC50: 530nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142584(N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H-pyrazol-3-yl]...)
Affinity DataIC50: 550nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142588(N-{4-[2-(4-Fluoro-phenyl)-5-trifluoromethyl-2H-pyr...)
Affinity DataIC50: 760nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142585(N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H-pyrazol-3-yl]...)
Affinity DataIC50: 770nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142586(N-{4-[2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-py...)
Affinity DataIC50: 960nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142581(N-{4-[2-(4-Amino-phenyl)-5-trifluoromethyl-2H-pyra...)
Affinity DataIC50: 2.64E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142590(N-[4-(2-Phenyl-5-trifluoromethyl-2H-pyrazol-3-yl)-...)
Affinity DataIC50: 2.90E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142580(N-{4-[2-(4-Dimethylamino-phenyl)-5-trifluoromethyl...)
Affinity DataIC50: 3.40E+3nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142592(N-{4-[2-(4-Bromo-phenyl)-5-trifluoromethyl-2H-pyra...)
Affinity DataIC50: 3.50E+3nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142591(N-{4-[2-(4-Bromo-phenyl)-5-trifluoromethyl-2H-pyra...)
Affinity DataIC50: 4.90E+3nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 7.81E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142593(N-{4-[5-Difluoromethyl-2-(4-fluoro-phenyl)-2H-pyra...)
Affinity DataIC50: 8.00E+3nMAssay Description:In vitro inhibitory activity against human recombinant prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.07E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142584(N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H-pyrazol-3-yl]...)
Affinity DataIC50: 1.33E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142589(N-{4-[2-(4-Chloro-phenyl)-5-trifluoromethyl-2H-pyr...)
Affinity DataIC50: 1.56E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142588(N-{4-[2-(4-Fluoro-phenyl)-5-trifluoromethyl-2H-pyr...)
Affinity DataIC50: 2.03E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142581(N-{4-[2-(4-Amino-phenyl)-5-trifluoromethyl-2H-pyra...)
Affinity DataIC50: 3.16E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142585(N-{4-[2-(4-Bromo-phenyl)-5-methyl-2H-pyrazol-3-yl]...)
Affinity DataIC50: 6.30E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142583(N-{4-[2-(4-Chloro-phenyl)-5-difluoromethyl-2H-pyra...)
Affinity DataIC50: 6.30E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142590(N-[4-(2-Phenyl-5-trifluoromethyl-2H-pyrazol-3-yl)-...)
Affinity DataIC50: 8.53E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50142587(N-{4-[2-(4-Chloro-phenyl)-5-methyl-2H-pyrazol-3-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 from the microsomal fraction of ram seminal vesiclesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed