Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50037303
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143796(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143792(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0200nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143786(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143802(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143797(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0300nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051007(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataKi:  0.0340nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143784(J-104132 | CHEMBL305576 | (5S,6R,7R)-5-Benzo[1,3]d...)
Affinity DataKi:  0.0340nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143783(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098777(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143778(2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-t...)
Affinity DataIC50: 0.0400nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143789(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143773(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0500nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143785(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143801(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0600nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143788(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143793(3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-...)
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143780(3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-...)
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143787(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0800nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143794(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.0900nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143774(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143772(2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-t...)
Affinity DataIC50: 0.110nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143790(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.140nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098772(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.150nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143781(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-5-met...)
Affinity DataIC50: 0.210nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143777({(2S,5S,8S,11R,14R,17S)-14-Carboxymethyl-11-(1H-in...)
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051007(4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2...)
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143799(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.390nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058126(2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-t...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143795(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 0.680nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143782(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 1.27nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143791(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 1.37nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058126(2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-t...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091105(4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethy...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058126(2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-t...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory concentration towards Endothelin A receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143798(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiop...)
Affinity DataIC50: 1.47nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143776(2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-t...)
Affinity DataIC50: 2.62nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061101(4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyph...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin receptor type B(Human)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50058126(2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-t...)
Affinity DataIC50: 9.80nMAssay Description:Inhibitory concentration towards endothelin B receptor in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143775(3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-5-met...)
Affinity DataIC50: 12.4nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Rat)
Encysive Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50143800(CHEMBL61780 | 5-Isopropyl-pyridine-2-sulfonic acid...)
Affinity DataIC50: 23nMAssay Description:Displacement of [125I]ET-1 from Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed