Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50014581
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144790((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 0.270nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144790((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144791((S)-3-[2-(2,6-Dichloro-phenyl)-benzooxazol-5-yl]-2...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144786((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144792((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144789((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144788((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Mn2+ activated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144786((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144792((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144789((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144791((S)-3-[2-(2,6-Dichloro-phenyl)-benzooxazol-5-yl]-2...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105372((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-2-met...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144791((S)-3-[2-(2,6-Dichloro-phenyl)-benzooxazol-5-yl]-2...)
Affinity DataIC50: 21nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144792((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 22nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144790((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 22nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144788((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 33nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144787((S)-2-(2,6-Dichloro-benzoylamino)-3-[2-(2,6-dichlo...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [Ca2+]/Mg2+ unactivated state of very late antigen 4 (VLA-4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144786((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 105nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144789((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 179nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144788((S)-2-{[(S)-1-(3,5-Dichloro-benzenesulfonyl)-azeti...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Mn2+ activated state of alpha4-beta7 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed