Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50037308
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50094569(Cyproterone 17-O-acetate | cyproterone acetate | C...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes without GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50094569(Cyproterone 17-O-acetate | cyproterone acetate | C...)
Affinity DataIC50: 125nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes with GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  150nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]R-PIA from adenosine A1 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataIC50: 680nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes without GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  680nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  1.13E+3nMAssay Description:Displacement of [3H]-MSX-2 from Adenosine A2A receptor of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]NECA from Adenosine A2A receptor of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataKi:  3.26E+3nMAssay Description:Displacement of [3H]CCPA from Adenosine A1 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in chinese hamster ovary cell membranes expressing human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataKi:  6.94E+3nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  8.20E+3nMAssay Description:Binding affinity towards human adenosine A2B receptor in VA13 fibroblasts as inhibition of adenylate cyclase at 10 uM; Less than 10% inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataKi:  9.45E+3nMAssay Description:Displacement of [3H]DPCPX from rat Adenosine A1 receptor of cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PSB-298 from human adenosine A2B receptor expressed in HEK293 cells at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50009685(CHEMBL65976 | 9-Methyl-9H-purin-6-ylamine | 9-Meth...)
Affinity DataIC50: 1.25E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes without GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataKi:  1.39E+4nMAssay Description:Displacement of [3H]PSB-298 from human adenosine A2B receptor expressed in HEK293 cells at 10 uM; Less than 10% inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50009685(CHEMBL65976 | 9-Methyl-9H-purin-6-ylamine | 9-Meth...)
Affinity DataIC50: 1.47E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes with GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataIC50: 1.51E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes with GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataKi:  1.71E+4nMAssay Description:Displacement of [3H]-MSX-2 from Adenosine A2A receptor of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataIC50: 2.30E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes without GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM21220(CHEMBL464859 | N-Ethylcarboxamidoadenosine | Adeno...)
Affinity DataIC50: 6.56E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in chinese hamster ovary cell membranes expressing human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfa...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in chinese hamster ovary cell membranes expressing human adenosine A3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50144902(3-(4-Hydroxy-phenyl)-2-methoxy-acrylic acid (3S,5R...)
Affinity DataIC50: 1.43E+5nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes with GTPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed