Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50014645
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | benzyl N-(4-{4-amino-1-[4-(4-methylp...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | benzyl N-(4-{4-amino-1-[4-(4-methylp...)
Affinity DataIC50: 13nMAssay Description:Inhibition of Src protein tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)
Affinity DataIC50: 20nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 24nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 28nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)
Affinity DataIC50: 37nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Src protein tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 57nMAssay Description:Inhibition of Src protein tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)
Affinity DataIC50: 64nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)
Affinity DataIC50: 70nMAssay Description:Inhibition of Src protein tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 93nMAssay Description:Inhibition of p56 Lck tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)
Affinity DataIC50: 97nMAssay Description:Inhibition of Src protein tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 155nMAssay Description:Inhibition of Src protein tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 189nMAssay Description:Inhibition of Src protein tyrosine kinase activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145570(1H-Indole-2-carboxylic acid (4-{4-amino-1-[4-(4-me...)
Affinity DataIC50: 520nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | benzyl N-(4-{4-amino-1-[4-(4-methylp...)
Affinity DataIC50: 521nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145572(3-{4-[(Furan-2-ylmethyl)-amino]-3-methoxy-phenyl}-...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 4.68E+3nMAssay Description:Inhibition of tyrosine protein kinase receptor TIE-2 with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8798(CHEMBL47787 | benzyl N-(4-{4-amino-1-[4-(4-methylp...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8807(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50145571(1-Methyl-1H-indole-2-carboxylic acid (4-{4-amino-1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8803(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM8797(N-(4-{4-amino-1-[4-(4-methylpiperazin-1-yl)cyclohe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2 activity with 1 mM ATP and biotinylated lck peptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed