Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 50014712
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146477(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146475(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146480(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylmethyl)-2...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146468(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146467(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146472(N-hydroxy-N-(1-(1-isobutylpiperidin-4-ylidene)-3-(...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146479(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexyl)-2-[4-(2...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146471(N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(2-methyl...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146469(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146470(N-Hydroxy-N-{1-(4-methylene-cyclohexyl)-2-[4-(2-me...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50146474(N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-[4-(2-methyl...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146471(N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(2-methyl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146471(N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(2-methyl...)
Affinity DataIC50: 280nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146480(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylmethyl)-2...)
Affinity DataIC50: 330nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 350nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146479(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexyl)-2-[4-(2...)
Affinity DataIC50: 500nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 550nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146480(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylmethyl)-2...)
Affinity DataIC50: 550nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146469(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146474(N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-[4-(2-methyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146474(N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-[4-(2-methyl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146473(2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-a...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146479(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexyl)-2-[4-(2...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146469(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(N-Hydroxy-N-{1-(4-methylene-cyclohexyl)-2-[4-(2-me...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146468(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146477(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146467(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146471(N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(2-methyl...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146480(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylmethyl)-2...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146475(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-17(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146472(N-hydroxy-N-(1-(1-isobutylpiperidin-4-ylidene)-3-(...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of matrix metalloprotease-17More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146478(N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146474(N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-[4-(2-methyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146477(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146470(N-Hydroxy-N-{1-(4-methylene-cyclohexyl)-2-[4-(2-me...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146474(N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-[4-(2-methyl...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146468(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146479(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexyl)-2-[4-(2...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146471(N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(2-methyl...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Kaken Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146469(N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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