Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50014858
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  0.790nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148370(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  1.06nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148369(1-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-pro...)
Affinity DataKi:  3.66nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148370(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  4.72nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  7.45nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148377(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  9.60nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148377(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  18.4nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148379(4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  63.9nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148379(4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  97.1nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  120nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  120nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148379(4-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  130nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148370(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  163nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148369(1-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-pro...)
Affinity DataKi:  235nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148377(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  240nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM84745(DULOXETINE | LY-248686 | CAS_136434-34-9 | LY24868...)
Affinity DataKi:  240nMAssay Description:Ability to inhibit [3H]WIN-35428 binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148378(2-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-pro...)
Affinity DataKi:  266nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148369(1-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-pro...)
Affinity DataKi:  353nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporter; Average of two experimentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  695nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  695nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148378(2-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-pro...)
Affinity DataKi:  920nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451958(CHEMBL2029052)
Affinity DataKi:  1.45E+3nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148378(2-Methoxy-5-((S)-3-methylamino-1-thiophen-2-yl-pro...)
Affinity DataKi:  2.81E+3nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148376(sodium 2-methoxy-5-{[(1S)-3-(methylamino)-1-thien-...)
Affinity DataKi:  3.11E+3nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451957(CHEMBL2029053)
Affinity DataKi:  3.50E+3nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451958(CHEMBL2029052)
Affinity DataKi:  5.45E+3nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi:  7.27E+3nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148373(5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naph...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148376(sodium 2-methoxy-5-{[(1S)-3-(methylamino)-1-thien-...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451955(CHEMBL2029055)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451957(CHEMBL2029053)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451956(CHEMBL2029054)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]paroxetine binding to cloned human serotonin (5-HT) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148376(sodium 2-methoxy-5-{[(1S)-3-(methylamino)-1-thien-...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451957(CHEMBL2029053)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451956(CHEMBL2029054)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451955(CHEMBL2029055)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]nisoxetine binding to cloned human norepinephrine (NE) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451958(CHEMBL2029052)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451956(CHEMBL2029054)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50451955(CHEMBL2029055)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit [3H]mazindol binding to cloned human dopamine (DA) transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed