Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50014956
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149521([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149515([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50054245(CHEMBL45281 | cid_176157 | 5-Chloro-N-cyclopropylm...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149518([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataKi:  13nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149515([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataKi:  15nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149528(Cyclopropylmethyl-[2-methyl-6-(2,4,6-trimethoxy-be...)
Affinity DataKi:  26nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149529([5-Allyl-6-(cyclopropylmethyl-propyl-amino)-2-meth...)
Affinity DataKi:  31nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149521([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataKi:  38nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149526((6-Diallylamino-2,5-dimethyl-pyrimidin-4-yl)-(2,4,...)
Affinity DataKi:  38nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149533([6-(Cyclopropylmethyl-propyl-amino)-5-ethyl-2-meth...)
Affinity DataKi:  55nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149522((6-Dipropylamino-2,5-dimethyl-pyrimidin-4-yl)-(2,4...)
Affinity DataKi:  58nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149541([6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyrim...)
Affinity DataKi:  79nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149532(Cyclopropylmethyl-{6-[methoxy-(2,4,6-triethyl-phen...)
Affinity DataKi:  90nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149520([2,5-Dimethyl-6-(phenyl-propyl-amino)-pyrimidin-4-...)
Affinity DataKi:  180nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149540([6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyrim...)
Affinity DataKi:  200nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149513([6-(1-Ethyl-propylamino)-2,5-dimethyl-pyrimidin-4-...)
Affinity DataKi:  220nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149539([6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyrim...)
Affinity DataKi:  360nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149519([6-((S)-2-Methoxymethyl-pyrrolidin-1-yl)-2,5-dimet...)
Affinity DataKi:  380nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149534([6-(Ethyl-phenyl-amino)-2,5-dimethyl-pyrimidin-4-y...)
Affinity DataKi:  470nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149530(Cyclopropylmethyl-{2-methyl-6-[1-(2,4,6-trimethoxy...)
Affinity DataKi:  480nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149536({6-[(2-Hydroxy-ethyl)-propyl-amino]-2,5-dimethyl-p...)
Affinity DataKi:  540nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149517(Cyclopropylmethyl-{2-methyl-6-[1-(2,4,6-trimethoxy...)
Affinity DataKi:  560nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149538([4-(Cyclopropylmethyl-propyl-amino)-6-methyl-pyrim...)
Affinity DataKi:  630nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149527([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataKi:  810nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149537([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataKi:  810nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149531([6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyrim...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149525({6-[Bis-(2-methoxy-ethyl)-amino]-2,5-dimethyl-pyri...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149524([6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyrim...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149535(1-[6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyr...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149542([6-(Cyclopropylmethyl-propyl-amino)-2,5-dimethyl-p...)
Affinity DataKi:  5.10E+3nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149512(Cyclopropylmethyl-{2-methyl-6-[1-methyl-1-(2,4,6-t...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149523([6-(Cyclopropylmethyl-propyl-amino)-2-methyl-pyrim...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149516((2,5-Dimethyl-6-pyrrolidin-1-yl-pyrimidin-4-yl)-(2...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Bioscience

Curated by ChEMBL
LigandPNGBDBM50149514((2,5-Dimethyl-6-morpholin-4-yl-pyrimidin-4-yl)-(2,...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed