Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50015076
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151035(4-{1-[3-(4-Oxo-3,4-dihydro-quinazolin-2-yl)-propyl...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151016(2-{3-[4-(4-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-...)
Affinity DataIC50: 8.30nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220864(2-(3-(4-(4-fluorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50: 8.90nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151013(2-{3-[4-(4-Pyridin-1-yl-phenyl)-3,6-dihydro-2H-pyr...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151012(2-{3-[4-(4-Hydroxy-phenyl)-3,6-dihydro-2H-pyridin-...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151025(2-[3-(1,4,5,6-Tetrahydro-2H-benzo[f]isoquinolin-3-...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151009(8-Methyl-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27705(2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)prop...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151038(5-Fluoro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151015(2-[3-(4-p-Tolyl-3,6-dihydro-2H-pyridin-1-yl)-propy...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151011(2-{3-[4-(3-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220868(2-(3-(4-(4-chlorophenyl)-5,6-dihydropyridin-1(2H)-...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151030(2-{3-[4-(4-Trifluoromethyl-phenyl)-3,6-dihydro-2H-...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27706(CHEMBL251029 | 8-chloro-2-[3-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151033(8-Methoxy-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151032(6-Chloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151023(2-[3-(4-Biphenyl-4-yl-3,6-dihydro-2H-pyridin-1-yl)...)
Affinity DataIC50: 34nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151019(2-{3-[4-(2-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1...)
Affinity DataIC50: 37nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151037(6,8-Dichloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin...)
Affinity DataIC50: 39nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220856(2-[3-(4-Phenyl-piperidin-1-yl)-propyl]-3H-quinazol...)
Affinity DataIC50: 46nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27714(CHEMBL361054 | 5-fluoro-1-[4-(4-phenyl-1,2,3,6-tet...)
Affinity DataIC50: 60nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27710(5-Chloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151022(8-Ethyl-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151031(2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-3H-quinazol...)
Affinity DataIC50: 71nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151010(2-[3-(1,3,4,9-Tetrahydro-beta-carbolin-2-yl)-propy...)
Affinity DataIC50: 74nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151014(2-{3-[4-(2-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151027(7-Chloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151036(2-{3-[4-(3-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151028(2-[3-(4-Phenyl-cyclohex-3-enyl)-propyl]-3H-quinazo...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50151026(2-(3-Piperidin-1-yl-propyl)-3H-quinazolin-4-one | ...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM27506(CHEMBL81977 | 3-aminobenzamide | 3-AB)
Affinity DataIC50: 1.12E+4nMAssay Description:In vitro inhibitory concentration against human recombinant Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed