Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50037454
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151216(difluoro(2-{[(2Z)-1-methyl-5-{2-[(5-{[5-({4-[4-(2-...)
Affinity DataKd:  13nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKd:  20nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151218(difluoro(2-{[(2Z)-1-methyl-5-(2-{[2-(2-{2-[4-(2-ox...)
Affinity DataKd:  4.10nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151213(difluoro(2-{[(2Z)-1-methyl-5-(2-{[5-({4-[4-(2-oxo-...)
Affinity DataKd:  14nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151212(difluoro(2-{[(2Z)-1-methyl-5-[2-({6-[4-(2-oxo-2-{1...)
Affinity DataKd:  13nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151215(2-[6-(diethylamino)-3-(diethyliminiumyl)-3H-xanthe...)
Affinity DataKd:  19nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151219(Cy3 derivative of pirenzepine, Cy3(15)PZ | (2E)-2-...)
Affinity DataKd:  36nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151214(difluoro(2-{[(2Z)-1-methyl-5-[2-({20-[4-(2-oxo-2-{...)
Affinity DataKd:  22nMAssay Description:Apparent dissociation constant for human muscarinic receptor M1 from FRET based binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151212(difluoro(2-{[(2Z)-1-methyl-5-[2-({6-[4-(2-oxo-2-{1...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151218(difluoro(2-{[(2Z)-1-methyl-5-(2-{[2-(2-{2-[4-(2-ox...)
Affinity DataKi:  8.90nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  24nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151214(difluoro(2-{[(2Z)-1-methyl-5-[2-({20-[4-(2-oxo-2-{...)
Affinity DataKi:  45nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151215(2-[6-(diethylamino)-3-(diethyliminiumyl)-3H-xanthe...)
Affinity DataKi:  54nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151216(difluoro(2-{[(2Z)-1-methyl-5-{2-[(5-{[5-({4-[4-(2-...)
Affinity DataKi:  55nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151213(difluoro(2-{[(2Z)-1-methyl-5-(2-{[5-({4-[4-(2-oxo-...)
Affinity DataKi:  70nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151219(Cy3 derivative of pirenzepine, Cy3(15)PZ | (2E)-2-...)
Affinity DataKi:  135nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151211(2,2-difluoro-12-[2-(methylcarbamoyl)ethyl]-4-(thio...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Umr Cnrs/Ulp 7081

Curated by ChEMBL
LigandPNGBDBM50151217(difluoro(2-{[(2Z)-1-methyl-5-[2-({2-[4-(2-oxo-2-{1...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of [3H]QNB binding to human muscarinic receptor M1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed