Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50037456
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151421(3-((E)-2-{4-[3-(2,6-Dichloro-phenyl)-5-isopropyl-i...)
Affinity DataEC50:  30nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21675(6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...)
Affinity DataEC50:  90nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151427((R)-4-((3R,6R,7R,10S,13R)-6-Allyl-3,7-dihydroxy-10...)
Affinity DataEC50:  480nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151420((R)-4-((3R,6R,7R,10S,13R)-3,7-Dihydroxy-10,13-dime...)
Affinity DataEC50:  540nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50117091(4-(3,7-Dihydroxy-6,10,13-trimethyl-hexadecahydro-c...)
Affinity DataEC50:  750nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151422((R)-4-((3R,6S,7S,10R,13R)-6-Fluoro-3,7-dihydroxy-1...)
Affinity DataEC50:  1.21E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151428(2-[(R)-3-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dime...)
Affinity DataEC50:  1.22E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50375577(CHEMBL270311)
Affinity DataEC50:  1.30E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151412((R)-2-[(S)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(R)-hydr...)
Affinity DataEC50:  2.43E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151416(ethyl 3-((3R,7R,10S,13R)-3,7-dihydroxy-10,13-dimet...)
Affinity DataEC50:  2.72E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151417(4-((4R,5S,9R,14R)-7-Hydroxy-3-(R)-hydroxy-10,13-di...)
Affinity DataEC50:  4.55E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151410(Sulfuric acid mono-[(R)-4-((3R,7R,10S,13R)-3,7-dih...)
Affinity DataEC50:  5.99E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataEC50:  8.66E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151419((3R,7R,10S,13R)-17-((R)-3-Amino-1-methyl-propyl)-1...)
Affinity DataEC50:  9.68E+3nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151424((1R,3R)-4-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dim...)
Affinity DataEC50:  1.02E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151429((1S,3R)-4-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dim...)
Affinity DataEC50:  1.32E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151430((R)-4-((3R,6R,7S,10R,13R)-3,7-Dihydroxy-6-methoxy-...)
Affinity DataEC50:  1.47E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151414((R)-4-((3R,6R,7S,10R,13R)-6-Fluoro-3,7-dihydroxy-1...)
Affinity DataEC50:  1.51E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151413((R)-4-((3R,6R,7R,10S,13R)-3,7-Dihydroxy-6,10,13-tr...)
Affinity DataEC50:  1.56E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151423(2-((4R,5S,9R,14S)-7-Hydroxy-3-(S)-hydroxy-10,13-di...)
Affinity DataEC50: >3.00E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151418((R)-4-((3R,6R,7S,10R,13R)-3,6,7-Trihydroxy-10,13-d...)
Affinity DataEC50: >3.00E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151431((R)-2-[(S)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(S)-hydr...)
Affinity DataEC50: >3.00E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151409((R)-2-[(R)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(R)-hydr...)
Affinity DataEC50: >3.00E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151415((3S,5R)-4-((3R,7R,10S,13R)-3,7-Dihydroxy-10,13-dim...)
Affinity DataEC50:  3.32E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151411((R)-2-[(R)-1-((3R,7R,10S,13R)-7-Hydroxy-3-(S)-hydr...)
Affinity DataEC50:  4.27E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50151425((R)-4-[(3R,6R,7R,10S,13R)-3,7-Dihydroxy-6-(2-hydro...)
Affinity DataEC50:  6.12E+4nMAssay Description:Binding affinity for human Farnesoid X receptor in FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed