Compile Data Set for Download or QSAR
Report error Found 141 Enz. Inhib. hit(s) with all data for entry = 50037354
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataEC50:  0.0900nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153127(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153124(N-(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl...)
Affinity DataKi:  5nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153121(1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-3,4-...)
Affinity DataKi:  6.10nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153132(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153137(3-Butyl-1-[1-(4-isopropyl-cyclohexyl)-piperidin-4-...)
Affinity DataKi:  18nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153127(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataEC50:  22nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  25nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153129(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)
Affinity DataKi:  29nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153132(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataEC50:  33nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153124(N-(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl...)
Affinity DataEC50:  34nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153121(1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-3,4-...)
Affinity DataEC50:  38nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153137(3-Butyl-1-[1-(4-isopropyl-cyclohexyl)-piperidin-4-...)
Affinity DataKi:  38nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153121(1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-3,4-...)
Affinity DataEC50:  38nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153123(1-[1-(1,4-Dimethyl-pentyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  40nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  41nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153141(1-(1-Indan-2-yl-piperidin-4-yl)-3,4-dihydro-1H-ben...)
Affinity DataKi:  46nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153122({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  63nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153123(1-[1-(1,4-Dimethyl-pentyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  73nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153137(3-Butyl-1-[1-(4-isopropyl-cyclohexyl)-piperidin-4-...)
Affinity DataEC50:  78nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153135(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  83nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153132(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataKi:  86nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153129(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)
Affinity DataKi:  92nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153127(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataKi:  92nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153124(N-(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl...)
Affinity DataKi:  106nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153129(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-3...)
Affinity DataEC50:  160nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataEC50:  166nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153125({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  182nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153128(1-(1-Cyclooctyl-piperidin-4-yl)-3,4-dihydro-1H-ben...)
Affinity DataKi:  187nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153134(1-[1-(4-Propyl-cyclohexyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  188nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  202nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153121(1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-3,4-...)
Affinity DataKi:  207nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153121(1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-3,4-...)
Affinity DataKi:  207nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153126(1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-1...)
Affinity DataKi:  225nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataEC50:  227nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153134(1-[1-(4-Propyl-cyclohexyl)-piperidin-4-yl]-3,4-dih...)
Affinity DataKi:  231nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153122({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataKi:  289nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153148(1-(1-Naphthalen-2-ylmethyl-piperidin-4-yl)-3,4-dih...)
Affinity DataKi:  294nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153131({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataEC50:  344nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153130(1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-1,3-...)
Affinity DataKi:  357nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153122({1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2...)
Affinity DataEC50:  484nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153141(1-(1-Indan-2-yl-piperidin-4-yl)-3,4-dihydro-1H-ben...)
Affinity DataEC50:  496nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153127(2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2...)
Affinity DataEC50:  555nMAssay Description:Agonist activity as stimulation of [35S]-GTP-gamma binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153148(1-(1-Naphthalen-2-ylmethyl-piperidin-4-yl)-3,4-dih...)
Affinity DataKi:  609nMAssay Description:Inhibition of [3H]nociceptin binding to human Opioid receptor like 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153141(1-(1-Indan-2-yl-piperidin-4-yl)-3,4-dihydro-1H-ben...)
Affinity DataKi:  660nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50153130(1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-1,3-...)
Affinity DataKi:  748nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
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