Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50015322
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154446(5-Hydroxy-2-(3-hydroxy-phenyl)-1-methyl-6-oxo-1,6-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154442(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50147498(3-Hydroxy-4-oxo-4H-pyran-2,6-dicarboxylic acid 6-e...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50115579(CHEMBL16326 | (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-e...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154446(5-Hydroxy-2-(3-hydroxy-phenyl)-1-methyl-6-oxo-1,6-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154442(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-RT is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154442(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154441(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154440(2-(3-Hydroxy-phenyl)-pyrimidine-4,5-diol | CHEMBL1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154445(5-Hydroxy-2-(3-hydroxy-phenyl)-6-methoxy-pyrimidin...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154443(2-(4-Chloro-phenyl)-6-hydroxy-5-methoxy-pyrimidine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154445(5-Hydroxy-2-(3-hydroxy-phenyl)-6-methoxy-pyrimidin...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-integrase is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154443(2-(4-Chloro-phenyl)-6-hydroxy-5-methoxy-pyrimidine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154440(2-(3-Hydroxy-phenyl)-pyrimidine-4,5-diol | CHEMBL1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mn2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154442(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-integrase is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-integrase is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration required to inhibit HIV-integrase is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase I(Escherichia coli (strain K12))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit HIV-RT is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase I(Escherichia coli (strain K12))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase I(Escherichia coli (strain K12))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154442(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit HIV-RT is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154444(2-(3-Benzyloxy-phenyl)-5,6-dihydroxy-pyrimidine-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit HIV-RT is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154441(2-(4-Chloro-phenyl)-5,6-dihydroxy-pyrimidine-4-car...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit HCV RNA dependent RNA polymerase Nonstructural protein 5B in the presence of Mg2+ is determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA polymerase I(Escherichia coli (strain K12))
Italy. Vinc

Curated by ChEMBL
LigandPNGBDBM50154439(5,6-Dihydroxy-2-(3-hydroxy-phenyl)-pyrimidine-4-ca...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration required to inhibit Klenow DNA-dependent DNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed