Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 50015355
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155213(1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-8-yl-u...)
Affinity DataIC50: 5nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155231(2-(1H-Benzoimidazol-5-yl)-N-(5-cyclobutyl-thiazol-...)
Affinity DataIC50: 7nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155209(1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-5-yl-u...)
Affinity DataIC50: 8nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155236(N-(5-Cyclobutyl-thiazol-2-yl)-2-quinolin-6-yl-acet...)
Affinity DataIC50: 10nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155235(N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-methyl-benzothi...)
Affinity DataIC50: 12nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155207(1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-5-yl-urea...)
Affinity DataIC50: 13nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155230(N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,6-dimethyl-benz...)
Affinity DataIC50: 13nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155237(N-(5-Cyclobutyl-thiazol-2-yl)-2-isoquinolin-5-yl-a...)
Affinity DataIC50: 13nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155214(N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H-indol-3-yl)-ac...)
Affinity DataIC50: 16nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155235(N-(5-Cyclobutyl-thiazol-2-yl)-2-(2-methyl-benzothi...)
Affinity DataIC50: 16nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155225(N-(5-cyclobutylthiazol-2-yl)-2-phenylacetamide | N...)
Affinity DataIC50: 25nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155236(N-(5-Cyclobutyl-thiazol-2-yl)-2-quinolin-6-yl-acet...)
Affinity DataIC50: 26nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155230(N-(5-Cyclobutyl-thiazol-2-yl)-2-(5,6-dimethyl-benz...)
Affinity DataIC50: 26nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155231(2-(1H-Benzoimidazol-5-yl)-N-(5-cyclobutyl-thiazol-...)
Affinity DataIC50: 33nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155214(N-(5-Cyclobutyl-thiazol-2-yl)-2-(1H-indol-3-yl)-ac...)
Affinity DataIC50: 40nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155232(1-(3H-Benzotriazol-4-yl)-3-(5-cyclobutyl-thiazol-2...)
Affinity DataIC50: 41nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155207(1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-5-yl-urea...)
Affinity DataIC50: 43nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155222(1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-6-yl-u...)
Affinity DataIC50: 44nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155221(1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-6-yl-urea...)
Affinity DataIC50: 44nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155220(N-(5-Cyclobutyl-thiazol-2-yl)-2-indol-1-yl-acetami...)
Affinity DataIC50: 48nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155213(1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-8-yl-u...)
Affinity DataIC50: 55nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155206(N-(5-Cyclopentyl-thiazol-2-yl)-2-phenyl-acetamide ...)
Affinity DataIC50: 64nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155210(N-(5-Isopropyl-thiazol-2-yl)-2-phenyl-acetamide | ...)
Affinity DataIC50: 64nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155237(N-(5-Cyclobutyl-thiazol-2-yl)-2-isoquinolin-5-yl-a...)
Affinity DataIC50: 70nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155225(N-(5-cyclobutylthiazol-2-yl)-2-phenylacetamide | N...)
Affinity DataIC50: 74nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155216(N-(5-Methylsulfanyl-thiazol-2-yl)-2-phenyl-acetami...)
Affinity DataIC50: 91nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155209(1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-5-yl-u...)
Affinity DataIC50: 96nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155210(N-(5-Isopropyl-thiazol-2-yl)-2-phenyl-acetamide | ...)
Affinity DataIC50: 98nMAssay Description:Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155220(N-(5-Cyclobutyl-thiazol-2-yl)-2-indol-1-yl-acetami...)
Affinity DataIC50: 100nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155234(1-(5-Isopropyl-thiazol-2-yl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50: 102nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155216(N-(5-Methylsulfanyl-thiazol-2-yl)-2-phenyl-acetami...)
Affinity DataIC50: 105nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155232(1-(3H-Benzotriazol-4-yl)-3-(5-cyclobutyl-thiazol-2...)
Affinity DataIC50: 106nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155206(N-(5-Cyclopentyl-thiazol-2-yl)-2-phenyl-acetamide ...)
Affinity DataIC50: 155nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155222(1-(5-Cyclobutyl-thiazol-2-yl)-3-isoquinolin-6-yl-u...)
Affinity DataIC50: 167nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155221(1-(5-Cyclobutyl-thiazol-2-yl)-3-quinolin-6-yl-urea...)
Affinity DataIC50: 167nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155211(1-(5-Cyclobutyl-thiazol-2-yl)-3-phenyl-urea | CHEM...)
Affinity DataIC50: 183nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155223(1-(5-Cyclobutyl-thiazol-2-yl)-3-(1H-indazol-7-yl)-...)
Affinity DataIC50: 190nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155234(1-(5-Isopropyl-thiazol-2-yl)-3-phenyl-urea | CHEMB...)
Affinity DataIC50: 265nMAssay Description:Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155211(1-(5-Cyclobutyl-thiazol-2-yl)-3-phenyl-urea | CHEM...)
Affinity DataIC50: 290nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155212(N-(5-Isopropyl-thiazol-2-yl)-isobutyramide | CHEMB...)
Affinity DataIC50: 318nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155212(N-(5-Isopropyl-thiazol-2-yl)-isobutyramide | CHEMB...)
Affinity DataIC50: 321nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155228(N-(5-Cyclohexyl-thiazol-2-yl)-2-phenyl-acetamide |...)
Affinity DataIC50: 390nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155226(N-(5-Ethyl-thiazol-2-yl)-2-phenyl-acetamide | CHEM...)
Affinity DataIC50: 412nMAssay Description:Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155227(N-(5-Bromo-thiazol-2-yl)-2-phenyl-acetamide | CHEM...)
Affinity DataIC50: 480nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155226(N-(5-Ethyl-thiazol-2-yl)-2-phenyl-acetamide | CHEM...)
Affinity DataIC50: 621nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155223(1-(5-Cyclobutyl-thiazol-2-yl)-3-(1H-indazol-7-yl)-...)
Affinity DataIC50: 650nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155227(N-(5-Bromo-thiazol-2-yl)-2-phenyl-acetamide | CHEM...)
Affinity DataIC50: 900nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155208((5-Isopropyl-thiazol-2-yl)-carbamic acid phenyl es...)
Affinity DataIC50: 980nMAssay Description:Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155228(N-(5-Cyclohexyl-thiazol-2-yl)-2-phenyl-acetamide |...)
Affinity DataIC50: 997nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155233(N-(5-Isopropyl-thiazol-2-yl)-benzamide | CHEMBL188...)
Affinity DataIC50: 1.02E+3nMAssay Description:Concentration required for 50% inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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