Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50015440
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156079(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-2-hydroxy-benzami...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156079(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-2-hydroxy-benzami...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156076(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-3,4-difluoro-benz...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156078(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-2-fluoro-benzamid...)
Affinity DataEC50:  75nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156063(3-Chloro-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamid...)
Affinity DataEC50:  200nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156062(Pyrazine-2-carboxylic acid (2,5-diphenyl-2H-pyrazo...)
Affinity DataEC50:  400nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156081(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-2-methyl-benzamid...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156068(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-4-trifluoromethyl...)
Affinity DataEC50:  19nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156066(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-3-methyl-benzamid...)
Affinity DataEC50:  90nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156078(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-2-fluoro-benzamid...)
Affinity DataEC50:  100nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156080(Thiophene-3-carboxylic acid (2,5-diphenyl-2H-pyraz...)
Affinity DataEC50:  1.80E+3nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156064(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-4-fluoro-benzamid...)
Affinity DataEC50:  30nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156080(Thiophene-3-carboxylic acid (2,5-diphenyl-2H-pyraz...)
Affinity DataEC50:  2.90E+3nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156077(4-Chloro-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamid...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156069(N-(1,3-diphenyl-1H-pyrazol-5-yl)-4-methylbenzamide...)
Affinity DataEC50:  30nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156067(Thiophene-2-carboxylic acid (2,5-diphenyl-2H-pyraz...)
Affinity DataEC50:  200nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156082(N-(4-bromo-2-((1,3-dioxoisoindolin-2-yl)methyl)phe...)
Affinity DataEC50:  740nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156075(Pyridine-2-carboxylic acid (2,5-diphenyl-2H-pyrazo...)
Affinity DataEC50:  585nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156062(Pyrazine-2-carboxylic acid (2,5-diphenyl-2H-pyrazo...)
Affinity DataEC50:  200nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156063(3-Chloro-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamid...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156064(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-4-fluoro-benzamid...)
Affinity DataEC50:  50nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156065(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-benzamide | N-(1,...)
Affinity DataEC50:  300nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156066(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-3-methyl-benzamid...)
Affinity DataEC50:  100nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156067(Thiophene-2-carboxylic acid (2,5-diphenyl-2H-pyraz...)
Affinity DataEC50:  400nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156068(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-4-trifluoromethyl...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156069(N-(1,3-diphenyl-1H-pyrazol-5-yl)-4-methylbenzamide...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156070(N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)ph...)
Affinity DataEC50:  300nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156061(Pyridine-2-carboxylic acid [4-chloro-2-(1,3-dioxo-...)
Affinity DataEC50:  245nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156072(2-Chloro-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamid...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156073(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-3-fluoro-benzamid...)
Affinity DataEC50:  65nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156074(N,N''-Bis-[1-(3-fluoro-phenyl)-meth-(E)-ylidene]-h...)
Affinity DataEC50:  2.36nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156075(Pyridine-2-carboxylic acid (2,5-diphenyl-2H-pyrazo...)
Affinity DataEC50:  290nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156076(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-3,4-difluoro-benz...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156065(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-benzamide | N-(1,...)
Affinity DataEC50:  40nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156073(N-(2,5-Diphenyl-2H-pyrazol-3-yl)-3-fluoro-benzamid...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156077(4-Chloro-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamid...)
Affinity DataEC50:  100nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed