Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50015485
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156503(8-Dibenzofuran-4-yl-2-morpholin-4-yl-chromen-4-one...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156498(2-(2-Methyl-morpholin-4-yl)-benzo[h]chromen-4-one ...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50098126(LY-293646 | 2-morpholino-4H-benzo[h]chromen-4-one ...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156502(2-morpholin-4-yl-8-thiophen-3-ylchromen-4-one | 2-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156500(8-(4-hydroxymethylphenyl)-2-morpholin-4-ylchromen-...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156496(2-Morpholin-4-yl-8-thiophen-2-yl-chromen-4-one | 2...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156497(8-(5-Acetyl-thiophen-2-yl)-2-morpholin-4-yl-chrome...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156499(8-benzo[b]thiophen-2-yl-2-morpholin-4-ylchromen-4-...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156501(8-(4-Methoxy-phenyl)-2-morpholin-4-yl-chromen-4-on...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50098118((2S,4R)-4-Mercapto-2-(2,4,5-trifluoro-benzyloxymet...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against DNA-dependent protein kinase (DNA-PK) at 0.5 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Mammalian target of Rapamycin mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Phosphatidylinositol 3-kinase p110 alpha subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mammalian target of Rapamycin mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Phosphatidylinositol 3-kinase p110 alpha subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50098126(LY-293646 | 2-morpholino-4H-benzo[h]chromen-4-one ...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Mammalian target of Rapamycin mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50098126(LY-293646 | 2-morpholino-4H-benzo[h]chromen-4-one ...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of Phosphatidylinositol 3-kinase p110 alpha subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Ataxia telangiectasia related protein ATR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50098126(LY-293646 | 2-morpholino-4H-benzo[h]chromen-4-one ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Ataxia telangiectasia related protein ATR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mutated in ataxia telangiectasia protein ATM kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50098126(LY-293646 | 2-morpholino-4H-benzo[h]chromen-4-one ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mutated in ataxia telangiectasia protein ATM kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ATR(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Ataxia telangiectasia related protein ATR kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50156495(NU-7441 | NU-7432 | 8-Dibenzothiophen-4-yl-2-morph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mutated in ataxia telangiectasia protein ATM kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed