Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50037847
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156570(1-[3-aminomethyl-3-deoxy-2-O-,6-N-(thiocarbonyl)-b...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156573(1-(3-aminomethyl-2-O-,6-N-carbonyl-3-deoxy-beta-D-...)
Affinity DataKi:  1.35E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50118625(Phosphoric acid mono-[4-chloro-3-hydroxy-5-(5-meth...)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM1(thymidine | dT)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156571(1-[3-(azidomethyl)-2,3-dideoxy-alpha-D-erythro-pen...)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156568(1,3-bis[(3R)-(3'-deoxythymidin-3'-yl)methyl]urea |...)
Affinity DataKi:  3.70E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156572(1-[3-C-(azido-methyl)-2,3-dideoxy-beta-D-thereo-pe...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50118623([(2R,3R,4R,5R)-4-fluoro-3-hydroxy-5-(5-methyl-2,4-...)
Affinity DataKi:  4.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131909(1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  5.70E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156576(1-(3-azidomethyl-2,5-difluoro-2,3,5-trideoxy-beta-...)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156574(1-(3-azidomethyl-2,3-dideoxy-2-fluoro-beta-D-ribof...)
Affinity DataKi:  1.65E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156575(1-(3-azidomethyl-2-chloro-2,3-dideoxy-beta-D-ribof...)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM1(thymidine | dT)
Affinity DataKi:  1.80E+5nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50131909(1-(4-Aminomethyl-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataKi:  2.20E+5nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156569(1-[3-aminomethyl-2-chloro-2,3-dideoxy-beta-D-ribof...)
Affinity DataKi:  3.90E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156570(1-[3-aminomethyl-3-deoxy-2-O-,6-N-(thiocarbonyl)-b...)
Affinity DataKi:  7.00E+5nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156572(1-[3-C-(azido-methyl)-2,3-dideoxy-beta-D-thereo-pe...)
Affinity DataKi:  1.04E+6nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed
TargetThymidylate kinase(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50156573(1-(3-aminomethyl-2-O-,6-N-carbonyl-3-deoxy-beta-D-...)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibition of human TMPK by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed