Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 2193
TargetRenin(Human)
Pfizer

LigandPNGBDBM17951((3S,4R)-4-(4-{3-[(2-methoxyphenyl)methoxy]propoxy}...)
Affinity DataIC50: 61nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17952((3S,4R)-N-[(6-methoxynaphthalen-2-yl)methyl]-4-(4-...)
Affinity DataIC50: 73nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17953(mixture of cis isomers | (3S,4R)-4-(4-{3-[(2-metho...)
Affinity DataIC50: 175nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17954(mixture of cis isomers | (3S,4R)-4-(4-{3-[(2-metho...)
Affinity DataIC50: 255nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17955(mixture of cis isomers | methyl 6-({[(3S,4R)-4-(4-...)
Affinity DataIC50: 282nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17956(mixture of cis isomers | (3S,4R)-N-(1-benzofuran-5...)
Affinity DataIC50: 393nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17957((3S,4R)-N-(1H-indol-5-ylmethyl)-4-(4-{3-[(2-methox...)
Affinity DataIC50: 2.28E+3nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17958(6-({[(3S,4R)-4-(4-{3-[(2-methoxyphenyl)methoxy]pro...)
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17959(mixture of cis isomers | N-[(3S,4R)-4-(4-{3-[(2-me...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

LigandPNGBDBM17960(mixture of cis isomers | (3S,4R)-4-(4-{3-[(2-metho...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2007
Entry Details Article
PubMed