Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 2667
TargetSphingosine 1-phosphate receptor 5(Human)
Mitsubishi Pharma

LigandPNGBDBM22202({[(4Z)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}phos...)
Affinity DataKi:  0.920nM ΔG°:  -47.9kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Mitsubishi Pharma

LigandPNGBDBM22202({[(4Z)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}phos...)
Affinity DataKi:  1.20nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Mitsubishi Pharma

LigandPNGBDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  2.10nM ΔG°:  -46.0kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 5(Human)
Mitsubishi Pharma

LigandPNGBDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  2.20nM ΔG°:  -45.9kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Mitsubishi Pharma

LigandPNGBDBM22202({[(4Z)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}phos...)
Affinity DataKi:  2.70nM ΔG°:  -45.5kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Mitsubishi Pharma

LigandPNGBDBM22202({[(4Z)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}phos...)
Affinity DataKi:  3.40nM ΔG°:  -44.9kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Mitsubishi Pharma

LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataKi:  4.10nM ΔG°:  -44.5kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Mitsubishi Pharma

LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataKi:  4.20nM ΔG°:  -44.4kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Mitsubishi Pharma

LigandPNGBDBM22202({[(4Z)-2-amino-3-hydroxyoctadec-4-en-1-yl]oxy}phos...)
Affinity DataKi:  5.40nM ΔG°:  -43.9kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Mitsubishi Pharma

LigandPNGBDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  5.90nM ΔG°:  -43.7kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSphingosine 1-phosphate receptor 3(Human)
Mitsubishi Pharma

LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataKi:  13nM ΔG°:  -41.8kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Mitsubishi Pharma

LigandPNGBDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  23nM ΔG°:  -40.5kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Mitsubishi Pharma

LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataKi:  37nM ΔG°:  -39.4kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Mitsubishi Pharma

LigandPNGBDBM23164(CHEMBL190006 | [(2R)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  105nM ΔG°:  -37.0kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Mitsubishi Pharma

LigandPNGBDBM23164(CHEMBL190006 | [(2R)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  121nM ΔG°:  -36.7kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Mitsubishi Pharma

LigandPNGBDBM23164(CHEMBL190006 | [(2R)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  277nM ΔG°:  -34.8kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Mitsubishi Pharma

LigandPNGBDBM23164(CHEMBL190006 | [(2R)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi:  586nM ΔG°:  -33.1kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Mitsubishi Pharma

LigandPNGBDBM23165(CHEMBL366208 | [(2S)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Mitsubishi Pharma

LigandPNGBDBM23164(CHEMBL190006 | [(2R)-2-amino-3-hydroxy-2-[2-(4-oct...)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Mitsubishi Pharma

LigandPNGBDBM23163({2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propo...)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.5 T: 2°CAssay Description:Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed