Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50015617
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091698((2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-c...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cell microsome assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158410(4-((+/-)-(1H-imidazol-1-yl)-N-(imidazolyl)-(E)-ret...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cell microsome assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091698((2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-c...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cells assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158410(4-((+/-)-(1H-imidazol-1-yl)-N-(imidazolyl)-(E)-ret...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cells assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091698((2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-c...)
Affinity DataIC50: 10.9nMAssay Description:Inhibition of ATRA-induced CYP26 in human MCF7 cells assessed ATRA as metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158411(4-((+/-)-(1H-imidazol-1-yl)-N-(4-hydroxyphenyl)-(E...)
Affinity DataIC50: 24nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cells assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158410(4-((+/-)-(1H-imidazol-1-yl)-N-(imidazolyl)-(E)-ret...)
Affinity DataIC50: 24.7nMAssay Description:Inhibition of ATRA-induced CYP26 in human MCF7 cells assessed ATRA as metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158415(4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate | ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cell microsome assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158411(4-((+/-)-(1H-imidazol-1-yl)-N-(4-hydroxyphenyl)-(E...)
Affinity DataIC50: 56nMAssay Description:Inhibition of ATRA-induced CYP26 in human MCF7 cells assessed ATRA as metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158415(4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate | ...)
Affinity DataIC50: 200nMAssay Description:Inhibition of ATRA-induced CYP26 in human MCF7 cells assessed ATRA as metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158415(4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate | ...)
Affinity DataIC50: 215nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cells assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158414((R,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6...)
Affinity DataIC50: 800nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cell microsome assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158414((R,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6...)
Affinity DataIC50: 800nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cell microsome assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [11,12-3H]ARTA from RARbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158414((R,2E,4E,6E,8E)-methyl 9-(3-(1H-imidazol-1-yl)-2,6...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ATRA-induced CYP26 in human T47D cells assessed as ATRA metabolism using [11.12-3H]-ATRAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataIC50: 9.00E+3nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158413(N-(1H-1,2,4-triazol-1-yl)-(E)-retinamide | CHEMBL3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091698((2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-c...)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158413(N-(1H-1,2,4-triazol-1-yl)-(E)-retinamide | CHEMBL3...)
Affinity DataIC50: 9.00E+4nMAssay Description:Displacement of [11,12-3H]ARTA from RARbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158416(4-((+/-)-(1H-imidazol-1-yl)-(13Z)-retinoic acid | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158416(4-((+/-)-(1H-imidazol-1-yl)-(13Z)-retinoic acid | ...)
Affinity DataIC50: 1.75E+5nMAssay Description:Displacement of [11,12-3H]ARTA from RARbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091698((2E,4E,6E,8E)-9-(3-Imidazol-1-yl-2,6,6-trimethyl-c...)
Affinity DataIC50: 1.75E+5nMAssay Description:Displacement of [11,12-3H]ARTA from RARbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091699((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-[1...)
Affinity DataIC50: 2.50E+5nMAssay Description:Displacement of [11,12-3H]ARTA from RARbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091699((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-[1...)
Affinity DataIC50: 4.10E+5nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158412(N-(1H-imidazole-1-yl)-(E)-retinamide | CHEMBL38806...)
Affinity DataIC50: 5.00E+5nMAssay Description:Displacement of [11,12-3H]ARTA from RARbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50158412(N-(1H-imidazole-1-yl)-(E)-retinamide | CHEMBL38806...)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor beta(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091700((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-[1...)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [11,12-3H]ARTA from RARbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor alpha(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50091700((2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-[1...)
Affinity DataIC50: 1.00E+6nMAssay Description:Displacement of [11,12-3H]ARTA from RARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed