Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 1377
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 18nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11160(Sitagliptin Analog 13 | (3R)-3-amino-4-(2,5-difluo...)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11161((1R)-3-(5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7...)
Affinity DataIC50: 68nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11163((1R)-1-(2,5-difluorobenzyl)-3-oxo-3-[3-(2,2,2-trif...)
Affinity DataIC50: 71nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11164(7-[(3R)-3-Amino-4-(2,5-difluorophenyl)butanoyl]-3-...)
Affinity DataIC50: 103nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11159((1R)-1-(3,4-difluorobenzyl)-3-oxo-3-[3-(trifluorom...)
Affinity DataIC50: 128nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11158((3R)-3-amino-4-(3,4-difluorophenyl)-1-{3-ethyl-5H,...)
Affinity DataIC50: 231nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM11157((3R)-3-amino-4-(3,4-difluorophenyl)-1-{5H,6H,7H,8H...)
Affinity DataIC50: 455nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11157((3R)-3-amino-4-(3,4-difluorophenyl)-1-{5H,6H,7H,8H...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11161((1R)-3-(5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7...)
Affinity DataIC50: 1.00E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11164(7-[(3R)-3-Amino-4-(2,5-difluorophenyl)butanoyl]-3-...)
Affinity DataIC50: 3.50E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11157((3R)-3-amino-4-(3,4-difluorophenyl)-1-{5H,6H,7H,8H...)
Affinity DataIC50: 3.80E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11158((3R)-3-amino-4-(3,4-difluorophenyl)-1-{3-ethyl-5H,...)
Affinity DataIC50: 4.50E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11159((1R)-1-(3,4-difluorobenzyl)-3-oxo-3-[3-(trifluorom...)
Affinity DataIC50: 4.60E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 4.80E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11158((3R)-3-amino-4-(3,4-difluorophenyl)-1-{3-ethyl-5H,...)
Affinity DataIC50: 6.40E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11160(Sitagliptin Analog 13 | (3R)-3-amino-4-(2,5-difluo...)
Affinity DataIC50: 6.90E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11161((1R)-3-(5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7...)
Affinity DataIC50: 7.20E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11163((1R)-1-(2,5-difluorobenzyl)-3-oxo-3-[3-(2,2,2-trif...)
Affinity DataIC50: 7.80E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM11163((1R)-1-(2,5-difluorobenzyl)-3-oxo-3-[3-(2,2,2-trif...)
Affinity DataIC50: 8.00E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11159((1R)-1-(3,4-difluorobenzyl)-3-oxo-3-[3-(trifluorom...)
Affinity DataIC50: 9.80E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11160(Sitagliptin Analog 13 | (3R)-3-amino-4-(2,5-difluo...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM11164(7-[(3R)-3-Amino-4-(2,5-difluorophenyl)butanoyl]-3-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11164(7-[(3R)-3-Amino-4-(2,5-difluorophenyl)butanoyl]-3-...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11163((1R)-1-(2,5-difluorobenzyl)-3-oxo-3-[3-(2,2,2-trif...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11161((1R)-3-(5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11162(Triazolopiperazine Analogue 1 | (3R)-3-amino-1-[3-...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11160(Sitagliptin Analog 13 | (3R)-3-amino-4-(2,5-difluo...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11159((1R)-1-(3,4-difluorobenzyl)-3-oxo-3-[3-(trifluorom...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11158((3R)-3-amino-4-(3,4-difluorophenyl)-1-{3-ethyl-5H,...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

LigandPNGBDBM11157((3R)-3-amino-4-(3,4-difluorophenyl)-1-{5H,6H,7H,8H...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/17/2006
Entry Details Article
PubMed