Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 1261
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10509(5-(1,2-dithiolan-3-yl)-N-[5-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 1.48nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10510(5-(1,2-dithiolan-3-yl)-N-[6-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 3.24nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10508(5-(1,2-dithiolan-3-yl)-N-[4-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 5.04nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10507(5-(1,2-dithiolan-3-yl)-N-[3-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 6.96nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10511(5-(1,2-dithiolan-3-yl)-N-[7-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 8.58nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10512(CHEMBL194823 | N-{3-[(6-chloro-1,2,3,4-tetrahydroa...)
Affinity DataIC50: 10.8nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10507(5-(1,2-dithiolan-3-yl)-N-[3-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 12nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 21.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10510(5-(1,2-dithiolan-3-yl)-N-[6-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 30.1nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10511(5-(1,2-dithiolan-3-yl)-N-[7-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 32.7nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10508(5-(1,2-dithiolan-3-yl)-N-[4-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 35.2nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10509(5-(1,2-dithiolan-3-yl)-N-[5-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 38.4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 45.8nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10506(5-(1,2-dithiolan-3-yl)-N-[2-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 47.5nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10506(5-(1,2-dithiolan-3-yl)-N-[2-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50: 97nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10513(N-[(9-amino-6-chloro-1,2,3,4-tetrahydroacridin-3-y...)
Affinity DataIC50: 329nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 424nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10513(N-[(9-amino-6-chloro-1,2,3,4-tetrahydroacridin-3-y...)
Affinity DataIC50: 1.09E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10514(N1-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)propan...)
Affinity DataIC50: 2.58E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10515(5-(1,2-dithiolan-3-yl)pentanoic acid | D,L-Lipoic ...)
Affinity DataIC50: 1.00E+6nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

LigandPNGBDBM10515(5-(1,2-dithiolan-3-yl)pentanoic acid | D,L-Lipoic ...)
Affinity DataIC50: 1.00E+6nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

LigandPNGBDBM10512(CHEMBL194823 | N-{3-[(6-chloro-1,2,3,4-tetrahydroa...)
Affinity DataKi:  155nM ΔG°:  -40.4kJ/mole IC50: 0.253nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2006
Entry Details Article
PubMed