Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50037428
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160730(3-{(S)-Methyl-[5-(4-trifluoromethyl-phenyl)-thioph...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160738(3-{[4-(4-Fluoro-phenoxy)-benzoyl]-methyl-amino}-py...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50150715(4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethyla...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160723(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  7.30nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160739(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160742(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160735(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160726(3-(3-Biphenyl-4-yl-1-methyl-ureido)-pyrrolidine-1-...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160722(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160732(3-{[5-(4-Chloro-phenyl)-5-oxo-pentanoyl]-methyl-am...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160728(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  57nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160746(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  64nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160727(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  64nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160745(3-{[2-(4-tert-Butyl-phenoxy)-acetyl]-methyl-amino}...)
Affinity DataKi:  67nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160724(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  75nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160729(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  82nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160731(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  83nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160734(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Affinity DataKi:  96nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160725(Biphenyl-4-carboxylic acid methyl-{3-[methyl-(1-me...)
Affinity DataKi:  142nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160730(3-{(S)-Methyl-[5-(4-trifluoromethyl-phenyl)-thioph...)
Affinity DataKi:  338nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160740(2-(4-Trifluoromethyl-phenyl)-thiazole-5-carboxylic...)
Affinity DataKi:  456nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160741(3-[1-Oxo-5-(4-trifluoromethyl-phenyl)-1,3-dihydro-...)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160736(3-{[4-(6-Methoxy-pyridazin-3-yl)-benzoyl]-methyl-a...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50160737(2-(4-Trifluoromethyl-phenyl)-3H-imidazole-4-carbox...)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed