Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50037546
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10616((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10610(CHEMBL361409 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10614(CHEMBL362444 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 4nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161789(Ethyl-carbamic acid 3a-methyl-2,3,3a,8a-tetrahydro...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10611(CHEMBL300143 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10617(CHEMBL362049 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 16nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10619((4-Isopropyl-phenyl)-carbamic acid (S)-3a,8-dimeth...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161786((4-Isopropyl-phenyl)-carbamic acid 1-methyl-8,10-d...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161787(o-Tolyl-carbamic acid 3a-methyl-2,3,3a,8a-tetrahyd...)
Affinity DataIC50: 23nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161790(Ethyl-carbamic acid 1-methyl-8,10-dioxa-tricyclo[7...)
Affinity DataIC50: 24nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161785((4-Isopropyl-phenyl)-carbamic acid 3a-methyl-2,3,3...)
Affinity DataIC50: 27nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10614(CHEMBL362444 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 27nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50004000(CHEMBL94 | physostigmine | Antilirium | Eserine | ...)
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50199522((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...)
Affinity DataIC50: 47nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 47nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10613((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161791(o-Tolyl-carbamic acid 1-methyl-8,10-dioxa-tricyclo...)
Affinity DataIC50: 56nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10616((3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8aH-furo[2,3-b]in...)
Affinity DataIC50: 82nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10610(CHEMBL361409 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 94nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM11686((-)-O-[(2-ethylphenyl)carbamoyl]geneseroline | Com...)
Affinity DataIC50: 125nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 190nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161789(Ethyl-carbamic acid 3a-methyl-2,3,3a,8a-tetrahydro...)
Affinity DataIC50: 360nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10613((3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo...)
Affinity DataIC50: 760nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161790(Ethyl-carbamic acid 1-methyl-8,10-dioxa-tricyclo[7...)
Affinity DataIC50: 830nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10617(CHEMBL362049 | (3aS)-3a,8-dimethyl-2H,3H,3aH,8H,8a...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM11686((-)-O-[(2-ethylphenyl)carbamoyl]geneseroline | Com...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10611(CHEMBL300143 | (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161785((4-Isopropyl-phenyl)-carbamic acid 3a-methyl-2,3,3...)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10619((4-Isopropyl-phenyl)-carbamic acid (S)-3a,8-dimeth...)
Affinity DataIC50: 3.86E+3nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161786((4-Isopropyl-phenyl)-carbamic acid 1-methyl-8,10-d...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50199522((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161791(o-Tolyl-carbamic acid 1-methyl-8,10-dioxa-tricyclo...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM50161787(o-Tolyl-carbamic acid 3a-methyl-2,3,3a,8a-tetrahyd...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed